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New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 1
作者:  Yue, Grace Gar-Lee;  Xie, Sida;  Lee, Julia Kin-Ming;  Kwok, Hin-Fai;  Gao, Si;  Nian, Yin;  Wu, Xiao-Xiao;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(2501Kb)  |  收藏  |  浏览/下载：275/55  |  提交时间：2016/12/21
The in Vitro and in Vivo Antitumor Activities of Tetracyclic Triterpenoids Compounds Actein and 26-Deoxyactein Isolated from Rhizome of Cimicifuga foetida L. 期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 8, 页码: 1001
作者:  Wu, Desong;  Yao, Qi;  Chen, Yajuan;  Hu, Xiaodong;  Qing, Chen;  Qiu, Minghua
浏览  |  Adobe PDF(2842Kb)  |  收藏  |  浏览/下载：207/34  |  提交时间：2017/01/05
Actein  26-deoxyactein  Antitumor Activity  Ic50  Cell Cycle  
Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear 期刊论文
FOOD CHEMISTRY, 2014, 卷号: 55, 期号: 47, 页码: 6490-6494
作者:  Peng,XingRong;  Liu,JieQing;  Wang,CuiFang;  Han,ZhongHui;  Shu,Yi;  Li,XuYang;  Zhou,Lin;  Qiu,MingHua;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  mhchiu@mail.kib.ac.cn
浏览  |  Adobe PDF(802Kb)  |  收藏  |  浏览/下载：333/93  |  提交时间：2015/01/20
Negative Regulator  Xenopus Embryos  C-cbl  Pathway  Protein  P53  Kinase  Degradation  Disease  Mechanisms  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
浏览  |  Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：214/41  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
Triterpenes from the Aerial Parts of Cimicifuga yunnanensis and Their Antiproliferative Effects on p53(N236S) Mouse Embryonic Fibroblasts 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 5, 页码: 896-902
作者:  Nian, Yin;  Zhu, Hui;  Tang, Wen-Ru;  Luo, Yin;  Du, Jiang;  Qiu, Ming-Hua
浏览  |  Adobe PDF(907Kb)  |  收藏  |  浏览/下载：280/75  |  提交时间：2013/07/24
Simplex Wormsk  9  19-cyclolanostane Derivatives  Cycloartane Triterpenoids  Constituents  Glycosides  Racemosa  Dahurica  Roots  
Cycloartane Triterpenoids from Cimicifuga yunnanensis induce Apoptosis of Breast Cancer Cells (MCF7) via p53-dependent Mitochondrial Signaling Pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 1, 页码: 17-24
作者:  Fang, Zhong-Ze;  Nian, Yin;  Li, Wei;  Wu, Jing-Jing;  Ge, Guang-Bo;  Dong, Pei-Pei;  Zhang, Yan-Yan;  Qiu, Ming-Hua;  Liu, Lei;  Yang, Ling
Adobe PDF(982Kb)  |  收藏  |  浏览/下载：352/121  |  提交时间：2012/04/10
Cycloartane Triterpenoids  Mcf7  P53  Apoptosis  Mitochondrial Membrane Potential  Caspase-7  
3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 5, 页码: 925-938
作者:  Yi, Ping;  Fang, Xin;  Qiu, Minghua
Adobe PDF(2704Kb)  |  收藏  |  浏览/下载：328/98  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  Comsia  Checkpoint Kinase Weel