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Microfractionation bioactivity-based ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of nuclear factor-kappa B inhibitors and beta(2) adrenergic receptor agonists in an alkaloidal extract of the folk herb Alstonia scholaris 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 卷号: 908, 页码: 98-104
作者:  Hou, Yuanyuan;  Cao, Xuelin;  Wang, Liqiang;  Cheng, Binfeng;  Dong, Linyi;  Luo, Xiaodong;  Bai, Gang;  Gao, Wenyuan
浏览  |  Adobe PDF(764Kb)  |  收藏  |  浏览/下载：325/92  |  提交时间：2013/01/22
Dual-bioactivity-integrated Fingerprinting  Constituent Identification  Nuclear Factor-kappa b Inhibitor  Beta(2) Adrenergic Receptor Agonist  Ultra Performance Liquid Chromatography/quadrupole Time-of-flight Mass Spectrometry  
A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2012, 卷号: 131, 期号: 6, 页码: 1445-1454
作者:  Feng, Chao;  Zhou, Li-Ying;  Yu, Ting;  Xu, Gang;  Tian, Hong-Lei;  Xu, Jin-Jie;  Xu, Hong-Xi;  Luo, Kathy Qian
浏览  |  Adobe PDF(1707Kb)  |  收藏  |  浏览/下载：345/92  |  提交时间：2012/11/30
Anticancer Drug Discovery  Herbal Medicine  Oblongifolin c  Apoptosis  Bax  
Senegalensions A-C, Three Limonoids from Khaya senegalensis 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2012, 卷号: 7, 期号: 9, 页码: 2024-2027
作者:  Yuan, Chun-Mao;  Zhang, Yu;  Tang, Gui-Hua;  Li, Shun-Lin;  Di, Ying-Tong;  Hou, Li;  Cai, Jie-Yun;  Hua, Hui-Ming;  He, Hong-Ping;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(499Kb)  |  收藏  |  浏览/下载：259/59  |  提交时间：2012/11/30
Biosynthesis  Computational Chemistry  Limonoids  Natural Products  Structure Elucidation  
Application of ultrahigh-performance liquid chromatography coupled with mass spectrometry for analysis of lignans and quality control of Fructus Schisandrae chinensis 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2012, 卷号: 35, 期号: 17, 页码: 2203-2209
作者:  Zhang, Wei-Dong;  Wang, Qing;  Wang, Ying;  Wang, Xiao-Juan;  Pu, Jian-Xin;  Gu, Yi;  Wang, Rong
浏览  |  Adobe PDF(719Kb)  |  收藏  |  浏览/下载：265/70  |  提交时间：2012/11/30
Fructus Schisandrae Chinensis  Lignans  Qualitative And Quantitative Analysis  Uhplc  Q-tof Ms  
Cytotoxic cycloartane triterpenes from the roots of Cimicifuga heracleifolia 期刊论文
TETRAHEDRON, 2012, 卷号: 68, 期号: 32, 页码: 6521-6527
作者:  Nian, Yin;  Wang, Hai-Yan;  Su, Jia;  Zhou, Lin;  Feng, Gang;  Li, Yan;  Qiu, Ming-Hua
浏览  |  Adobe PDF(524Kb)  |  收藏  |  浏览/下载：777/314  |  提交时间：2012/09/03
Cimicifuga Heracleifolia  Cycloartane Triterpenes  Cytotoxicity  Structure-activity Relationships  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(719Kb)  |  收藏  |  浏览/下载：444/143  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Hypoglycemia and Death in Mice Following Experimental Exposure to an Extract of Trogia venenata Mushrooms 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 6, 页码: e38712
作者:  Shi, GuoQing;  He, Jun;  Shen, Tao;  Fontaine, Robert E.;  Yang, Lin;  Zhou, ZhongYu;  Gao, Hong;  Xu, YanFeng;  Qin, Chuan;  Yang, ZhuLiang;  Liu, JiKai;  Huang, WenLi;  Zeng, Guang
浏览  |  Adobe PDF(81Kb)  |  收藏  |  浏览/下载：225/50  |  提交时间：2014/04/02
Multicomplex-Based Pharmacophore-Guided 3D-QSAR Studies of N-Substituted 2'-(Aminoaryl)Benzothiazoles as Aurora-A Inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2012, 卷号: 79, 期号: 6, 页码: 960-971
作者:  He, Gu;  Qiu, Minghua;  Li, Rui;  Ouyang, Liang;  Wu, Fengbo;  Song, Xiangrong;  Cheng, Li;  Xiang, Mingli;  Yu, Luoting
Adobe PDF(1377Kb)  |  收藏  |  浏览/下载：299/92  |  提交时间：2012/06/07
3d-qsar  Aurora-a  Kinase Inhibitors  Multicomplex-based Pharmacophore(Mcbp)  Pharmacophore  
Tianma modulates proteins with various neuro-regenerative modalities in differentiated human neuronal SH-SY5Y cells 期刊论文
NEUROCHEMISTRY INTERNATIONAL, 2012, 卷号: 60, 期号: 8, 页码: 827-836
作者:  Ramachandran, Umamaheswari;  Manavalan, Arulmani;  Sundaramurthi, Husvinee;  Sze, Siu Kwan;  Feng, Zhi Wei;  Hu, Jiang-Miao;  Heese, Klaus
浏览  |  Adobe PDF(1419Kb)  |  收藏  |  浏览/下载：428/120  |  提交时间：2012/09/03
Tianma  Neuron  Herb  Tcm  Itraq  Neurodegeneration  
Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 10, 页码: 3473-3479
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Chen, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(5043Kb)  |  收藏  |  浏览/下载：413/185  |  提交时间：2012/06/07
Glycyrrhetinic Acid Derivatives  Anti-hbv Activity  Structure-activity Relationships