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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：225/45  |  提交时间：2020/03/26
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：312/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：213/55  |  提交时间：2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Molecular cloning and characterization of the glutathione reductase gene from Stipa purpurea 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 495, 期号: 2, 页码: 1851-1857
作者:  Wang, Qiuli;  Pu, Yanan;  Yang, Danni;  Yin, Xin;  He, Zhaorong;  Yang, Yunqiang;  Yang, Yongping
Adobe PDF(2793Kb)  |  收藏  |  浏览/下载：204/47  |  提交时间：2018/05/08
Stipa Purpurea  Glutathione Reductase  Gssg  Gsh  Salinity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：455/206  |  提交时间：2017/02/28
Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans 期刊论文
AGING-US, 2017, 卷号: 9, 期号: 2, 页码: 447-474
作者:  Wan, Qin-Li;  Shi, Xiaohuo;  Liu, Jiangxin;  Ding, Ai-Jun;  Pu, Yuan-Zhu;  Li, Zhigang;  Wu, Gui-Sheng;  Luo, Huai-Rong
Adobe PDF(4040Kb)  |  收藏  |  浏览/下载：193/54  |  提交时间：2017/05/19
Caenorhabditis Elegans  Aging  Reproduction  Metabolome  Uplc-ms And Nmr  
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
Adobe PDF(1121Kb)  |  收藏  |  浏览/下载：473/62  |  提交时间：2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin  
Eriocalyxin B-Induced Apoptosis in Pancreatic Adenocarcinoma Cells Through Thiol-Containing Antioxidant Systems and Downstream Signalling Pathways 期刊论文
CURRENT MOLECULAR MEDICINE, 2014, 卷号: 14, 期号: 5, 页码: 673-689
作者:  Li, L.;  Yue, G. G. L.;  Pu, J. X.;  Sun, H. D.;  Fung, K. P.;  Leung, P. C.;  Han, Q. B.;  Lau, C. B. S.;  Leung, P. S.;  Xu, JC (reprint author), Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Yunnan, Peoples R China.;  j.c.xu@cgiar.org;  kdhyde3@gmail.com
Adobe PDF(998Kb)  |  收藏  |  浏览/下载：283/100  |  提交时间：2014/10/11
Apoptosis  Eriocalyxin b  Pancreatic Cancer  Reactive Oxygen Species  Thiols  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：319/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer