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Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
浏览  |  Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：255/56  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
ent-Kauranoids isolated from Isodon eriocalyx var. laxiflora and their structure activity relationship analyses 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 48, 页码: 9161-9171
作者:  Wang,Wei-Guang;  Yang,Jin;  Wu,Hai-Yan;  Kong,Ling-Mei;  Su,Jia;  Li,Xiao-Nian;  Du,Xue;  Zhan,Rui;  Zhou,Min;  Li,Yan;  Pu,Jian-Xin;  Sun,Han-Dong
浏览  |  Adobe PDF(1109Kb)  |  收藏  |  浏览/下载：241/60  |  提交时间：2016/01/19
Ent-kaurane  Diterpenoids  Isodon  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：306/80  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
浏览  |  Adobe PDF(1124Kb)  |  收藏  |  浏览/下载：332/67  |  提交时间：2013/11/12
Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation  
Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with beta-Catenin/TCF4 Interaction in Colorectal Cancer Cells 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 7, 页码: e68525
作者:  Li, Xingyao;  Pu, Jianxin;  Jiang, Shiyou;  Su, Jia;  Kong, Lingmei;  Mao, Bingyu;  Sun, Handong;  Li, Yan
浏览  |  Adobe PDF(1775Kb)  |  收藏  |  浏览/下载：579/108  |  提交时间：2013/10/16
Beta-catenin  Colon-cancer  Response Element  Activation  Expression  Pathway  Complex  Growth  Apc  Antagonists  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：325/72  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Rubiyunnanins C-H, cytotoxic cyclic hexapeptides from Rubia yunnanensis inhibiting nitric oxide production and NF-kappa B activation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 卷号: 18, 期号: 23, 页码: 8226-8234
作者:  Fan, Jun-Ting;  Su, Jia;  Peng, Yan-Min;  Li, Yan;  Li, Jia;  Zhou, Yu-Bo;  Zeng, Guang-Zhi;  Yan, He;  Tan, Ning-Hua
Adobe PDF(424Kb)  |  收藏  |  浏览/下载：417/177  |  提交时间：2012/03/21
Rubia Yunnanensis  Rubiyunnanins C-h  Cyclopeptides  Cytotoxicity  Inhibition Of No Production  Nf-kappa b Pathway Inhibitors