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Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα 期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2023, 卷号: 21, 期号: 5, 页码: 1274-1288
作者:  Shen,Chuanbin;  Mackeigan,Daniel T.;  Shoara,Aron A.;  Xu,Runjia;  Bhoria,Preeti;  Karakas,Danielle;  Ma,Wenjing;  Cerenzia,Eric;  Chen,ZiYan;  Hoard,Brock;  Lin,Lisha;  Lei,Xi;  Zhu,Guangheng;  Chen,Pingguo;  Johnson,Philip E.;  Ni,Heyu
浏览  |  Adobe PDF(4055Kb)  |  收藏  |  浏览/下载:97/8  |  提交时间:2024/07/22
fucoidan  glycoprotein Ib  platelet  thrombosis  von Willebrand factor  VON-WILLEBRAND-FACTOR  PLATELET GLYCOPROTEIN IB  MOLECULAR-WEIGHT FUCOIDAN  ARTERIAL THROMBOSIS  IX  AGGREGATION  RECEPTOR  ACTIVATION  FIBRINOGEN  INTEGRIN  
Isolation and identification of hemostatic steroidal glycosides from Ypsilandra thibetica 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 106268
作者:  Ma,Wen-Yi;  Xie,Jing;  Yu,Ling-Ling;  Zhang,Shi-Juan;  Ni,Wei;  Yan,Huan;  Liu,Hai-Yang
浏览  |  Adobe PDF(2307Kb)  |  收藏  |  浏览/下载:95/17  |  提交时间:2024/07/22
Ypsilandra thibetica  Steroidal saponins  Ypsilandrosides Z1-Z14  Hemostatic activity  Structure-activity relationship  SPIROSTANE GLYCOSIDES  NMR-SPECTROSCOPY  AGGREGATION  SAPOGENINS  SAPONINS  
Artemannuols A-C, novel sesquiterpenoid-flavonol hybrids with antihepatoma activity from Artemisia annua 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 26, 页码: 5451-5456
作者:  He,Xiao-Feng;  Wang,Meng-Fei;  Li,Tian-Ze;  Ma,Yun-Bao;  Chen,Ji-Jun
浏览  |  Adobe PDF(556Kb)  |  收藏  |  浏览/下载:109/17  |  提交时间:2024/07/25
Hepatocellular-carcinoma  Aggregation Pheromone  Bug  
Natural Coumarin Isomers with Dramatically Different AIE Properties: Mechanism and Application 期刊论文
ACS CENTRAL SCIENCE, 2023, 卷号: 9, 期号: 5, 页码: 883-891
作者:  Chen,Shan-Shan;  Wang,Haoran;  Wu,Bo;  Li,Qiyao;  Gong,Junyi;  Zhao,Yun-Li;  Zhao,Yun;  Xiao,Xia;  Lam,Jacky W. Y.;  Zhao,Zheng;  Luo,Xiao-Dong;  Tang,Ben Zhong
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AGGREGATION-INDUCED EMISSION  AIEGENS  ABSORPTION  CHEMISTRY  
重楼属中富含偏诺甾体皂苷的植物资源挖掘及其研究 学位论文
: 中国科学院大学, 2022
作者:  余玲玲
Adobe PDF(11095Kb)  |  收藏  |  浏览/下载:99/0  |  提交时间:2024/05/14
重楼属 (Paris L.),黑药花科,偏诺皂苷,球药隔重楼,LC-MS/MS,诱导血小板聚集活性  Paris L., Melanthiaceae, Pennogenin saponins, Paris fargesii, LC-MS/MS, Inducing platelet aggregation activity  
岩藻糖化糖胺聚糖 系统给药的毒性作用及其相关的血小板激活作用与机制 学位论文
: 中国科学院大学, 2022
作者:  林丽莎
Adobe PDF(5816Kb)  |  收藏  |  浏览/下载:131/0  |  提交时间:2024/05/14
岩藻糖化糖胺聚糖,毒性机制,血小板聚集,构效关系,血小板受体  Fucosylated glycosaminoglycan, Toxic effect, Platelet aggregation, Structure-activity relationship, Platelet receptor  
抗血小板活性松香烷二萜的合成、结构优化及机制研究 学位论文
: 中国科学院大学, 2022
作者:  夏凡
Adobe PDF(4437Kb)  |  收藏  |  浏览/下载:101/0  |  提交时间:2024/05/14
康定鼠尾草,松香烷二萜,抗血小板活性,合成和结构优化研究  Salvia prattii, Abietane diterpenoid, Antiplatelet aggregation activity, Synthesis and structure optimization  
Multifunctional Anti-Alzheimer's Disease Effects of Natural Xanthone Derivatives: A Primary Structure-Activity Evaluation 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10, 页码: 842208
作者:  Hu, Xiaoyu;  Liu, Chan;  Wang, Kaichun;  Zhao, Lanxue;  Qiu, Yu;  Chen, Hongzhuan;  Hu, Jiangmiao;  Xu, Jianrong
浏览  |  Adobe PDF(2230Kb)  |  收藏  |  浏览/下载:63/7  |  提交时间:2024/08/21
alpha-mangostin  Alzheimer's disease  multifunctional  structure-activity  neuroinflammation  amyloid beta  BETA-AMYLOID PEPTIDES  BLOOD-BRAIN-BARRIER  CENTRAL-NERVOUS-SYSTEM  ALPHA-MANGOSTIN  MICROGLIA  OLIGOMERS  AGGREGATION  MODULATION  PRODUCTS  DESIGN  
New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth 期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 104875
作者:  Qin,Jing;  Liao,Chao-Nan;  Chen,Wei-wei;  Li,Hong-you;  Su,Jia;  Wu,Xing-De;  He,Jiang-bo;  Zhang,Gao-hong
收藏  |  浏览/下载:145/0  |  提交时间:2022/04/02
Limonoid  Quinolone alkaloid  Cytotoxic activity  Anti-platelet aggregation  Evodia rutaecarpa (Juss  ) Benth  FRUITS  
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
作者:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
浏览  |  Adobe PDF(2854Kb)  |  收藏  |  浏览/下载:217/33  |  提交时间:2022/04/02
fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS