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Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：17/4  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-2H-indolin-2-one Derivatives 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 12, 页码: 4668
作者:  Pan,Taohua;  He,Maofei;  Deng,Lulu;  Li,Jiang;  Fan,Yanhua;  Hao,Xiaojiang;  Mu,Shuzhen
浏览  |  Adobe PDF(3057Kb)  |  收藏  |  浏览/下载：50/11  |  提交时间：2024/05/09
oxindoles  alpha,beta-unsaturated ketone  anti-inflammatory  COX-2 inhibitory activity  ANTIINFLAMMATORY ACTIVITY  NATURAL-PRODUCTS  OXINDOLE-DERIVATIVES  NITRIC-OXIDE  POTENT  CYCLOOXYGENASE-2  DISCOVERY  PAIN  LIABILITY  
Recent Studies on Protective Effects of Walnuts against Neuroinflammation 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 20, 页码: 4360
作者:  Tan, Bing;  Wang, Yuxi;  Zhang, Xudong;  Sun, Xiangjun
浏览  |  Adobe PDF(999Kb)  |  收藏  |  浏览/下载：105/12  |  提交时间：2024/04/30
walnuts  neuroinflammation  neurodegenerative diseases  oxidative stress  antioxidant activity  gut microbes  ALPHA-LINOLENIC ACID  BETA-AMYLOID PROTEIN  NF-KAPPA-B  OXIDATIVE STRESS  COGNITIVE IMPAIRMENT  MEDITERRANEAN DIET  INDUCED ACTIVATION  BV-2 MICROGLIA  ELLAGIC ACID  GALLIC ACID  
Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 4, 页码: 1076-1079
作者:  Wang, Lu;  Xu, Chen;  Chen, Li;  Hao, Xiaojiang;  Wang, David Zhigang
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Beta-hydroxy Ketones  Nitrile Oxide Cycloaddition  Daphniphyllum Alkaloids  Tetracyclic Core  Daphnilactone-b  Ring-system  Construction  Reduction  Delta-2-isoxazolines  Route  
A new Amaryllidaceae alkaloid from the bulbs of Lycoris radiata 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2013, 卷号: 11, 期号: 4, 页码: 406-410
作者:  Huang Sheng-Dian;  Zhang Yu;  He Hong-Ping;  Li Shi-Fei;  Tang Gui-Hua;  Chen Duo-Zhi;  Cao Ming-Ming;  Di Ying-Tong;  Hao Xiao-Jiang
浏览  |  Adobe PDF(606Kb)  |  收藏  |  浏览/下载：316/66  |  提交时间：2013/10/16
Lycoris Radiata  Amaryllidaceae Alkaloids  Homolycorine-type  2 Alpha-methoxy-6-o-methyloduline  2 Alpha-methoxy-6-beta-ethyloduline  
Microfractionation bioactivity-based ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of nuclear factor-kappa B inhibitors and beta(2) adrenergic receptor agonists in an alkaloidal extract of the folk herb Alstonia scholaris 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 卷号: 908, 页码: 98-104
作者:  Hou, Yuanyuan;  Cao, Xuelin;  Wang, Liqiang;  Cheng, Binfeng;  Dong, Linyi;  Luo, Xiaodong;  Bai, Gang;  Gao, Wenyuan
浏览  |  Adobe PDF(764Kb)  |  收藏  |  浏览/下载：356/101  |  提交时间：2013/01/22
Dual-bioactivity-integrated Fingerprinting  Constituent Identification  Nuclear Factor-kappa b Inhibitor  Beta(2) Adrenergic Receptor Agonist  Ultra Performance Liquid Chromatography/quadrupole Time-of-flight Mass Spectrometry  
Bioactivity-based liquid chromatography-coupled electrospray ionization tandem ion trap/time of flight mass spectrometry for beta(2)AR agonist identification in alkaloidal extract of Alstonia scholaris 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2012, 卷号: 1227, 页码: 203-209
作者:  Hou, Yuanyuan;  Cao, Xuelin;  Dong, Linyi;  Wang, Liqiang;  Cheng, Binfeng;  Shi, Qian;  Luo, Xiaodong;  Bai, Gang
Adobe PDF(949Kb)  |  收藏  |  浏览/下载：563/197  |  提交时间：2012/06/07
Bioactivity-integrated Fingerprinting  Constituent Identification  Beta(2) Adrenergic Receptor Agonist  Lcms-it-tof  
A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2012, 卷号: 10, 期号: 1, 页码: 24-27
作者:  Fang Ping-Lei;  Liu Hai-Yang;  Zhong Hui-Min
Adobe PDF(285Kb)  |  收藏  |  浏览/下载：350/88  |  提交时间：2012/06/07
Acute Promyelocytic Leukemia  Activated Protein-kinase  Retinoic Acid  Signal-transduction  Alpha Oncoprotein  Pmlrar-alpha  C/ebp-beta  Product  Stress  H2o2  
Michael Addition between Isatin and Acrylate Derivatives 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2011, 卷号: 8, 期号: 9, 页码: 614-617
作者:  Chen, Gang;  Tang, Ying;  Zhang, Jie;  Wu, Ya;  Hao, Xiao-Jiang;  Mu, Shu-Zhen
浏览  |  Adobe PDF(164Kb)  |  收藏  |  浏览/下载：581/326  |  提交时间：2012/07/25
Acrylate  Isatin  Beta-(2  Michael Addition  3-dioxoindolin-1-yl) Propanoate  
A New Chromene Isolated from Ageratum conyzoides 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2011, 卷号: 6, 期号: 9, 页码: 1263-1265
作者:  Adebayo, Abiodun Humphrey;  Ji, Chang-Jiu;  Zhang, Yu-Mei;  He, Wen-Jun;  Zeng, Guang-Zhi;  Han, Hong-Jin;  Xu, Jun-Ju;  Akindahunsi, Afolabi Akintunde;  Tan, Ning-Hua
浏览  |  Adobe PDF(81Kb)  |  收藏  |  浏览/下载：300/86  |  提交时间：2012/07/25
Ageratum Conyzoides  Compositae  Cytotoxicity  2  2-dimethylchromene 7-methoxy-6-o-beta-d-glucopyranoside