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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
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Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L. 期刊论文
TETRAHEDRON LETTERS, 2023, 卷号: 123, 页码: 154550
作者:  Huang,Jian-Yi;  Yang,Ying;  Liang,Hong;  Pu,Xue-Xue;  Li,Ying-Yao;  Cai,Min;  Guo,Feng;  Liu,Lin;  Cao,Ming-Ming;  Yan,Ying;  Cheng,Yuanyuan;  Di,Ying-Tong;  Hao,Xiao-Jiang
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Anti-inflammatory  Pepluane  Diterpenoid  Euphorbia peplus L  Chemical transformation  DISCOVERY  PARALIANE  INSIGHTS  PROFILE  LATEX  
Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L. 期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 61-66
作者:  Guan,Shi-Peng;  Yang,Ying;  Sun,Mao;  Cai,Min;  Pu,Xue-Xue;  Huang,Jian-Yi;  Yi,Ping;  Liu,Lin;  Yuan,Ming-Rui;  Cheng,Yuan-Yuan;  Di,Ying-Tong
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Diterpenoids  Lathyrane  Anti-inflammatory activity  DP4+  Euphorbia peplus  Dexamethasone  CASBANE DITERPENOIDS  JATROPHANE DITERPENOIDS  MODULATORS  ROOTS  
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 659, 页码: 10-19
作者:  Zhu,Yiying;  Zhao,Zhangxun;  Xue,Minggao;  Wang,Dan;  Su,Guifeng;  Ju,Xiaoman;  Yang,Qihong;  Zhang,Shaohua;  Fan,Dongmei;  Zhu,Huifang;  Yu,Min;  Li,Yan;  Kong,Lingmei;  Zhou,Hongyu
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Ciclopirox olamine  Natural killer cells  NKG2D ligands  Immunotherapy  LIGANDS  RECEPTOR  GROWTH  
Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum 期刊论文
FITOTERAPIA, 2023, 卷号: 165, 页码: 105402
作者:  Guo,Kai;  Ren,Xue;  Zhou,Ting-Ting;  Li,Tao;  Liu,Yan-Chun;  Tao,Yang;  Hu,Hong;  Li,Dan;  Liu,Yan;  Li,Sheng-Hong
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Lomatogonium carinthiacum  Gentianaceae  Monoterpenoids  Monoterpenoid alkaloids  Sesquiterpenoids  Immunosuppressive activity  STRUCTURAL ELUCIDATION  GLYCOSIDES  SECOIRIDOIDS  GLUCOSIDE  PART  
Heterodimers with a cucurbitane-type triterpenoid skeleton from the branches of Elaeocarpus dubius 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 207, 页码: 113581
作者:  Hu,Dong-Bao;  Wei,Shu-Ya;  Yang,Jun;  Zhang,Dong-Dong;  Duan,Xiao-Yan;  Yan,Hui;  Yang,Xing-Zhi;  Bai,Xue;  Luo,Ji-Feng;  Yang,Jing-Hua;  Wang,Yun-Song;  Wang,Yue-Hu
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Elaeocarpus dubius  Elaeocarpaceae  Cucurbitacins  Antioxidant  Neuroprotective  CONSTITUENTS  ELUCIDATION  GLYCOSIDES  
Diversity of medicinal plants and their therapeutic usages of Kachin people (Jinghpaw) in the central part of Kachin State, Myanmar 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 302, 期号: B, 页码: 115921
作者:  Hein,Pyae Phyo;  Arunachalam,Karuppusamy;  Fu,Yao;  Zaw,Moe;  Yang,Yongping;  Yang,Xuefei
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Ethnobotany  Medicinal plants  Traditional knowledge  Kachin people  Myanmar  ETHNOMEDICINAL PLANTS  AQUILARIA-MALACCENSIS  CHROMOLAENA-ODORATA  TRADITIONAL USES  PHYTOCHEMISTRY  KNOWLEDGE  AGARWOOD  EXTRACT  
Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
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astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
Comparative transcriptomes reveal the disjunction adaptive strategy of Thuja species in East Asia and North America 期刊论文
JOURNAL OF FORESTRY RESEARCH, 2023, 卷号: 34, 期号: 6, 页码: 1963-1974
作者:  Chang,Ermei;  Liu,Xue;  Chen,Jiahui;  Sun,Jingyi;  Yang,Shaowei;  Liu,Jianfeng
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Thuja species  Comparative transcriptomes  East Asia-North America disjunction  Specific gene  Positively selected gene  FLAVONOID BIOSYNTHESIS  PLANT  SUTCHUENENSIS  DIVERSITY  MARKERS  
Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 11, 页码: 4638-4654
作者:  Chen,Yuegui;  Yan,Qin;  Ji,Yunheng;  Bai,Xue;  Li,Desen;  Mu,Rongfang;  Guo,Kai;  Yang,Minjie;  Tao,Yang;  Gershenzon,Jonathan;  Liu,Yan;  Li,Shenghong
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Paris polyphylla var. yunnanensis  Steroidal saponins  Glycosyltransferases  Sugar chain elongation  Antifungal activity  CHEMICAL-CONSTITUENTS  GLYCOSYLTRANSFERASES  GLYCOSIDES  DIVERSITY  CULTIVATION  PATHWAY  FAMILY  PARTS  GENUS  STEP