Knowledge Management System of Kunming Institute of Botany,CAS
Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L. | |
Guan,Shi-Peng; Yang,Ying; Sun,Mao; Cai,Min; Pu,Xue-Xue; Huang,Jian-Yi; Yi,Ping; Liu,Lin; Yuan,Ming-Rui; Cheng,Yuan-Yuan; Di,Ying-Tong | |
2023 | |
发表期刊 | PHYTOCHEMISTRY LETTERS |
ISSN | 1876-7486 |
卷号 | 55页码:61-66 |
摘要 | Euphpepluone S (1), a new lathyrane diterpenoid, was isolated and characterized from Euphorbia peplus. The structure of 1 was established by extensive spectroscopic analysis, NMR calculations with DP4+ analyses, and ECD calculations. Notably, compound 1 significantly suppressed the levels of NO, IL-1fi, IL-6 and TNF alpha in LPS-induced RAW264.7 cells at 20 mu M, which showed comparable bioactivity as the positive control-dexamethasone. |
关键词 | Diterpenoids Lathyrane Anti-inflammatory activity DP4+ Euphorbia peplus Dexamethasone CASBANE DITERPENOIDS JATROPHANE DITERPENOIDS MODULATORS ROOTS |
学科领域 | Plant Sciences ; Pharmacology & Pharmacy |
DOI | 10.1016/j.phytol.2023.03.011 |
收录类别 | SCI |
WOS记录号 | WOS:000972504400001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/75425 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Guan,Shi-Peng,Yang,Ying,Sun,Mao,et al. Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.[J]. PHYTOCHEMISTRY LETTERS,2023,55:61-66. |
APA | Guan,Shi-Peng.,Yang,Ying.,Sun,Mao.,Cai,Min.,Pu,Xue-Xue.,...&Di,Ying-Tong.(2023).Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L..PHYTOCHEMISTRY LETTERS,55,61-66. |
MLA | Guan,Shi-Peng,et al."Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.".PHYTOCHEMISTRY LETTERS 55(2023):61-66. |
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