Knowledge Management System of Kunming Institute of Botany,CAS
| Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L. | |
| Guan,Shi-Peng; Yang,Ying; Sun,Mao; Cai,Min; Pu,Xue-Xue; Huang,Jian-Yi; Yi,Ping; Liu,Lin; Yuan,Ming-Rui; Cheng,Yuan-Yuan; Di,Ying-Tong | |
| 2023 | |
| Source Publication | PHYTOCHEMISTRY LETTERS
 |
| ISSN | 1876-7486 |
| Volume | 55Pages:61-66 |
| Abstract | Euphpepluone S (1), a new lathyrane diterpenoid, was isolated and characterized from Euphorbia peplus. The structure of 1 was established by extensive spectroscopic analysis, NMR calculations with DP4+ analyses, and ECD calculations. Notably, compound 1 significantly suppressed the levels of NO, IL-1fi, IL-6 and TNF alpha in LPS-induced RAW264.7 cells at 20 mu M, which showed comparable bioactivity as the positive control-dexamethasone. |
| Keyword | Diterpenoids Lathyrane Anti-inflammatory activity DP4+ Euphorbia peplus Dexamethasone CASBANE DITERPENOIDS JATROPHANE DITERPENOIDS MODULATORS ROOTS |
| Subject Area | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1016/j.phytol.2023.03.011 |
| Indexed By | SCI |
| WOS ID | WOS:000972504400001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/75425 |
| Collection | 中国科学院昆明植物研究所 |
| Recommended Citation GB/T 7714 | Guan,Shi-Peng,Yang,Ying,Sun,Mao,et al. Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.[J]. PHYTOCHEMISTRY LETTERS,2023,55:61-66. |
| APA | Guan,Shi-Peng.,Yang,Ying.,Sun,Mao.,Cai,Min.,Pu,Xue-Xue.,...&Di,Ying-Tong.(2023).Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L..PHYTOCHEMISTRY LETTERS,55,61-66. |
| MLA | Guan,Shi-Peng,et al."Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.".PHYTOCHEMISTRY LETTERS 55(2023):61-66. |
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| 1-s2.0-S187439002300（1957KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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