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Oligosaccharide-assisted resolution of holothurian fucosylated chondroitin sulfate for fine structure and P-selectin inhibition 期刊论文
CARBOHYDRATE POLYMERS, 2025, 卷号: 351, 页码: 123145
作者:  Pan, Ying;  Sun, Huifang;  Gu, Xi;  Li, Sujuan;  Yang, Shengtao;  Zhang, Liang;  Mao, Hui;  Wang, Pin;  Yang, Shasha;  Yin, Ronghua;  Zuo, Zhili;  Zhao, Jinhua
浏览  |  Adobe PDF(7292Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Deciphering fungal metabolon coupling tandem inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids 期刊论文
SCIENCE CHINA-CHEMISTRY, 2025, 卷号: 68, 期号: 1, 页码: 288-296
作者:  Liu, Shuai;  Xu, Wen-Qiang;  Di, Ying-Tong;  Tang, Man-Cheng;  Chen, Ding-Kang;  Cao, Ming-Ming;  Chang, Yao-Wen;  Tang, Hong-Yu;  Yuan, Chun-Mao;  Yang, Jun-Bo;  Zuo, Zhi-Li;  Guo, Han;  Xu, Zi-Fei;  Zeng, Ying;  Wu, Yun-Dong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1777Kb)  |  收藏  |  浏览/下载：1/1  |  提交时间：2025/10/20
Structural optimization and bioactivity evaluation of 2-(Methylcarbonylamino) thiazole derivatives as novel PDE4B inhibitors 期刊论文
TETRAHEDRON, 2024, 卷号: 167, 页码: 134250
作者:  Ma, Rui;  Song, Na;  Gu, Xi;  Guo, Rong;  Shen, Meiling;  Zhang, Shuqun;  Yang, Weimin;  Zuo, Zhili
浏览  |  Adobe PDF(11203Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Identification of novel GSPT1 degraders by virtual screening and bioassay 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 273, 页码: 116524
作者:  Zhang, Shuqun;  Nie, Shiyun;  Ma, Guangchao;  Shen, Meiling;  Kong, Lingmei;  Zuo, Zhili;  Li, Yan
浏览  |  Adobe PDF(12264Kb)  |  收藏  |  浏览/下载：1/0  |  提交时间：2025/10/20
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
浏览  |  Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：833/517  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 124, 页码: 108567
作者:  Ma,Rui;  Song,Na;  Wang,Lveli;  Gu,Xi;  Xiong,Feng;  Zhang,Shuqun;  Zhang,Jie;  Yang,Weimin;  Zuo,Zhili
浏览  |  Adobe PDF(5778Kb)  |  收藏  |  浏览/下载：530/370  |  提交时间：2024/07/22
PHOSPHODIESTERASE-4 INHIBITOR  ACCURATE DOCKING  APREMILAST  EFFICACY  INSIGHTS  DISEASE  ASTHMA  POTENT  GLIDE  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：531/310  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：161/39  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPARα agonists by in silico studies and biochemical evaluation 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 2256867
作者:  Li,Yue;  Lv,Mengjia;  Shen,Meiling;  Gu,Xi;  Zhang,Li;  Liu,Xingyong;  Chen,Jing;  Gong,Likun;  Zuo,Zhili
浏览  |  Adobe PDF(3338Kb)  |  收藏  |  浏览/下载：558/388  |  提交时间：2024/07/31
NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation  FATTY-ACID OXIDATION  GROMACS  
INDITTO2 transposon conveys auxin-mediated DRO1 transcription for rice drought avoidance 期刊论文
PLANT CELL AND ENVIRONMENT, 2021, 卷号: 44, 期号: 6, 页码: 1846-1857
作者:  Zhao,Yiting;  Wu,Lixia;  Fu,Qijing;  Wang,Dong;  Li,Jing;  Yao,Baolin;  Yu,Si;  Jiang,Li;  Qian,Jie;  Zhou,Xuan;  Han,Li;  Zhao,Shuanglu;  Ma,Canrong;  Zhang,Yanfang;  Luo,Chongyu;  Dong,Qian;  Li,Saijie;  Zhang,Lina;  Jiang,Xi;  Li,Youchun;  Luo,Hao;  Li,Kuixiu;  Yang,Jing;  Luo,Qiong;  Li,Lichi;  Peng,Sheng;  Huang,Huichuan;  Zuo,Zhili;  Liu,Changning;  Wang,Lei;  Li,Chengyun;  He,Xiahong;  Friml,Jiri;  Du,Yunlong
收藏  |  浏览/下载：377/0  |  提交时间：2022/04/02
DNA transposable elements  indoleacetic acid  Oryza  stress