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Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-34
作者:  Fang Qiu;  Chun-Yu Qiu;  Huilan Cai;  Ting-Ting Liu;  Zu-Wei Qu;  Zhifan Yang;  Jia-Da Li;  Qun-Yong Zhou;  Wang-Ping Hu
Adobe PDF(850Kb)  |  收藏  |  浏览/下载:251/1  |  提交时间:2017/07/24
Oxytocin  Acid-sensing Ion Channel  Proton-gated Current  Vasopressin-1a Receptor  Dorsal Root Ganglion Neuron  Electrophysiology  Pain  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
作者:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  收藏  |  浏览/下载:174/1  |  提交时间:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载:109/1  |  提交时间:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
虚拟筛选与蛋白降解在TRPC5调节剂发现设计中的实践 学位论文
, 2021
作者:  刘斌
Microsoft Word(8818Kb)  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/03/20
Discovery of novel modulators targeting human TRPC5: Docking-based virtual screening, molecular dynamics simulation and binding af fi nity predication 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 102, 页码: 107795
作者:  Liu,Bin;  Zhang,Wei;  Guo,Sheng;  Zuo,Zhili
浏览  |  Adobe PDF(4277Kb)  |  收藏  |  浏览/下载:80/10  |  提交时间:2022/04/02
hTRPC5  Homology modeling  Molecular docking  Molecular dynamics simulation  Virtual screening  INHIBITOR  CHANNELS  GROMACS  POTENT  AMBER  IDENTIFICATION  CONSTRAINTS  INTEGRATION  AMYGDALA  
菟丝子与寄主间蛋白质大规模转运研究 学位论文
, 2020
作者:  刘念
Adobe PDF(5689Kb)  |  收藏  |  浏览/下载:16/0  |  提交时间:2023/11/02
Identification of Novel TRPC5 Inhibitors by Pharmacophore-Based and Structure-Based Approaches 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2020
作者:  Li, Shuxiang;  Zhang, Shuqun;  Chen, Dingyuan;  Jiang, Xuan;  Liu, Bin;  Zhang, Hongbin;  Rachakunta, Munikishore;  Zuo, Zhili
浏览  |  Adobe PDF(4261Kb)  |  收藏  |  浏览/下载:133/33  |  提交时间:2021/01/05
AS160功能结构域的鉴定及新型促GLUT4转运药物筛选模型的应用 学位论文
硕士: 中国科学院昆明植物研究所, 2019
作者:  马秀丽
Adobe PDF(2723Kb)  |  收藏  |  浏览/下载:40/0  |  提交时间:2022/08/29
AS160  CBD结构域  胰岛β细胞  GLUT4  药物筛选  
Progress in Understanding the Physiological and Molecular Responses of Populus to Salt Stress 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 6, 页码: 17
作者:  Zhang, Xiaoning;  Liu, Lijun;  Chen, Bowen;  Qin, Zihai;  Xiao, Yufei;  Zhang, Ye;  Yao, Ruiling;  Liu, Hailong;  Yang, Hong
Adobe PDF(428Kb)  |  收藏  |  浏览/下载:177/46  |  提交时间:2019/05/24
poplars (Populus)  salt tolerance  molecular mechanisms  SOS  ROS  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
Adobe PDF(3409Kb)  |  收藏  |  浏览/下载:194/51  |  提交时间:2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging