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Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
浏览  |  Adobe PDF(5002Kb)  |  收藏  |  浏览/下载：17/1  |  提交时间：2024/05/09
astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 209
作者:  Yu,Zhiyin;  Huang,Jian-Ping;  Yang,Jing;  Liu,Chongxi;  Yan,Yijun;  Wang,Li;  Zhao,Junwei;  Chen,Yin;  Xiang,Wensheng;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/05/09
HYPERTENSION  PREDICTION  FLAVIN  MECHANISM  PATHWAY  OXIDASE  COMPLEX  DOMAIN  SOIL  
黄素单加氧酶 VibMO1 的酶学性质及其分子改造 学位论文
: 中国科学院大学, 2022
作者:  戚芳婷
Adobe PDF(4511Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/14
黄素单加氧酶，VibMO1，酶学性质，催化机理，分子改造  Flavin monooxygenase, VibMO1, Enzymatic properties, Catalytic mechanism, Molecular engineering  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：119/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
真菌烯化吲哚生物碱的生物合成及Perforalactone CD 促溶酶体生成研究 学位论文
, 2021
作者:  刘帅
Adobe PDF(20692Kb)  |  收藏  |  浏览/下载：25/0  |  提交时间：2024/03/20
Tropane alkaloid biosynthesis: a centennial review 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 9, 页码: 1634-1658
作者:  Huang,Jian-Ping;  Wang,Yong-Jiang;  Tian,Tian;  Wang,Li;  Yan,Yijun;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(2786Kb)  |  收藏  |  浏览/下载：123/34  |  提交时间：2022/04/02
PUTRESCINE N-METHYLTRANSFERASE  TRANSFORMED ROOT CULTURES  2 TROPINONE REDUCTASES  ROLLE DES ACETATS  DATURA-STRAMONIUM  HYOSCYAMUS-NIGER  TOBACCO ALKALOIDS  ORNITHINE-DECARBOXYLASE  2-OXOGLUTARATE-DEPENDENT DIOXYGENASE  DIFFERENT STEREOSPECIFICITIES  
Discovery and heterologous production of sarubicins and quinazolinone C-glycosides with protecting activity for cardiomyocytes 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 14, 页码: 3829-3837
作者:  Yu,Mingming;  Luo,Jianying;  Luo,Dan;  He,Qiang;  Yan,Yijun;  Ji,Xu;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(1404Kb)  |  收藏  |  浏览/下载：123/35  |  提交时间：2022/04/02
STREPTOMYCES-VIOLACEORUBER TU22  BIOSYNTHESIS  GRANATICIN  ANTIBIOTICS  METABOLISM  MECHANISM  PATHWAY  ACID  
The untapped potential of plant sesterterpenoids: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 12, 页码: 2293-2314
作者:  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(3431Kb)  |  收藏  |  浏览/下载：79/22  |  提交时间：2022/04/02
LEUCOSCEPTRUM-CANUM  GLANDULAR TRICHOMES  FERN CONSTITUENTS  AERIAL PARTS  ABSOLUTE STEREOCHEMISTRY  SALVIA  CYCLIZATION  SYNTHASES  NORSESTERTERPENES  CONFIGURATION  
Side Products of Recombinant Amorpha-4,11-diene Synthase and Their Effect on Microbial Artemisinin Production 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 7, 页码: 2168-2178
作者:  Huang,Jin-Quan;  Li,Dong-Mei;  Tian,Xiu;  Lin,Jia-Ling;  Yang,Lei;  Xu,Jing-Jing;  Fang,Xin
浏览  |  Adobe PDF(2211Kb)  |  收藏  |  浏览/下载：74/23  |  提交时间：2022/04/02
artemisinin  chiral analysis  cytochrome P450 monooxygenases  labeling  sesquiterpenes  specialized metabolism pathway  terpene synthases  
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 30, 页码: 6650-6656
作者:  Huang,Jin-Quan;  Li,Dong-Mei;  Li,Jian-Xu;  Lin,Jia-Ling;  Tian,Xiu;  Wang,Ling-Jian;  Chen,Xiao-Ya;  Fang,Xin
浏览  |  Adobe PDF(2357Kb)  |  收藏  |  浏览/下载：76/18  |  提交时间：2022/04/02
ACTIVE-SITE RESIDUES  ARISTOLOCHENE SYNTHASE  ARTEMISIA-ANNUA  BIOLOGY  IDENTIFICATION  BIOSYNTHESIS  EXPRESSION  CLONING  GENES