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An Approach for the Synthesis of Pyrazolo[1,5-a]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 18, 页码: 12762-12771
作者:  Ren,Jian;  Ding,Shihua;  Li,Xiaonian;  Bi,Ran;  Zhao,Qinshi
浏览  |  Adobe PDF(1469Kb)  |  收藏  |  浏览/下载：89/19  |  提交时间：2022/04/02
BIOLOGICAL EVALUATION  REGIOSELECTIVE SYNTHESIS  CASCADE REACTIONS  FUNCTIONALIZATION  DEHYDROGENATION  DISCOVERY  POTENT  BOND  SAR  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：383/42  |  提交时间：2017/12/18
Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：312/72  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Synthesis of a Small-Molecule Library with Skeletal Diversity from Hemslecin A via the Reaction-Discovery Strategy 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 16, 页码: 3948-3951
作者:  Ren, Jian;  Shi, Xin;  Li, Xiao-Nian;  Li, Lai-Wei;  Su, Jia;  Shao, Li-Dong;  Zhao, Qin-Shi
浏览  |  Adobe PDF(390Kb)  |  收藏  |  浏览/下载：179/60  |  提交时间：2016/11/04
Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation 期刊论文
CANCER RESEARCH, 2016, 卷号: 76, 期号: 9, 页码: 2698-2709
作者:  Yu, Zu-Yin;  Xiao, He;  Wang, Li-Mei;  Shen, Xing;  Jing, Yu;  Wang, Lin;  Sun, Wen-Feng;  Zhang, Yan-Feng;  Cui, Yu;  Shan, Ya-Jun;  Zhou, Wen-Bing;  Xing, Shuang;  Xiong, Guo-Lin;  Liu, Xiao-Lan;  Dong, Bo;  Feng, Jian-Nan;  Wang, Li-Sheng;  Luo, Qing-Liang;  Zhao, Qin-Shi;  Cong, Yu-Wen
Adobe PDF(1368Kb)  |  收藏  |  浏览/下载：287/95  |  提交时间：2016/08/22
Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum 期刊论文
FITOTERAPIA, 2016, 卷号: 109, 页码: 224-229
作者:  He, Juan;  Peng, Li-Yan;  Tu, Lin;  Wu, Xing-De;  Dong, Liao-Bing;  Pan, Zheng-Hong;  Chen, Xuan-Qin;  Su, Jia;  Zhao, Yu;  Xu, Gang;  Cheng, Xiao;  Li, Yan;  Zhao, Qin-Shi
Adobe PDF(446Kb)  |  收藏  |  浏览/下载：264/86  |  提交时间：2016/08/22
Viburnum Odoratissimum  Vibsane-type Diterpenes  Vibsanols C-h  Vibsanin x  Cytotoxicity  
Natural product vibsanine A induces differentiation of myeloid leukemia cells through PKC activation 期刊论文
Cancer Research, 2016, 期号: 1, 页码: 1
作者:  Zhao QS(赵勤实)
Adobe PDF(1368Kb)  |  收藏  |  浏览/下载：142/46  |  提交时间：2017/02/28
Synthesis of hupehenols A, B, and E from protopanaxadiol 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 42, 页码: 35792-35803
作者:  Shao, Li-Dong;  Xu, Jun;  Li, Xiao-Nian;  Zhang, Zhi-Jun;  Shi, Xin;  Ren, Jian;  He, Juan;  Zhao, Yu;  Leng, Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(1402Kb)  |  收藏  |  浏览/下载：224/61  |  提交时间：2016/08/22
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
Adobe PDF(1516Kb)  |  收藏  |  浏览/下载：278/43  |  提交时间：2015/07/20
Isolation and Complete Structural Assignment of Lycopodium Alkaloid Cernupalhine A: Theoretical Prediction and Total Synthesis Validation 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 10, 页码: 2700-2703
作者:  Dong, Liao-Bin;  Wu, Ya-Nan;  Jiang, Shi-Zhi;  Wu, Xing-De;  He, Juan;  Yang, Yu-Rong;  Zhao, Qin-Shi
Adobe PDF(319Kb)  |  收藏  |  浏览/下载：348/56  |  提交时间：2014/06/23
Fawcettimine-related Alkaloids  Alpha  Unified Total Syntheses  Beta-unsaturated Carbonyl-compounds  Palhinhaea-cernua  Unprecedented Skeleton  Helquist Annulation  A-c  Japonicum  (-)-8-deoxyserratinine  (+)-lycoflexine