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Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载:224/51  |  提交时间:2020/03/18
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载:252/37  |  提交时间:2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载:434/191  |  提交时间:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:378/42  |  提交时间:2017/12/18
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载:383/90  |  提交时间:2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 3, 页码: 1599-1611
作者:  Wan, Wei-Chao;  Chen, Wen;  Liu, Lan-Xiang;  Li, Yan;  Yang, Li-Juan;  Deng, Xiao-Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(509Kb)  |  收藏  |  浏览/下载:786/524  |  提交时间:2014/04/09
Hybrid Compound  Benzofuran  Imidazole  Cytotoxic Activity  Structure-activity Relationships  Molecular Docking  
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Yan, Ju-Ming;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Zhou, Bei;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(3339Kb)  |  收藏  |  浏览/下载:344/144  |  提交时间:2013/10/16
Hybrid Compound  Imidazole  Dibenzo[b  Antitumor Activities  d]Furan  Structure-activity Relationships  
Novel Tricyclic Indeno[5,6-b] furan-imidazole Hybrid Compounds: Design, Synthesis and Antitumor Activity 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 卷号: 10, 期号: 7, 页码: 561-571
作者:  Chen, Wen;  Yang, Li-Juan;  Li, Yan;  Wang, Xue-Quan;  Wang, Shao-Jie;  Wan, Wei-Chao;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Unknown(243Kb)  |  收藏  |  浏览/下载:238/3  |  提交时间:2013/10/16
Hybrid Compound  Imidazole  Synthesis  Indeno[5  Cytotoxic Activity  6-b]Furan  Structure-activity Relationships  
Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 15, 页码: 4297-4302
作者:  Chen, Wen;  Deng, Xiao-Yan;  Li, Yan;  Yang, Li-Juan;  Wan, Wei-Chao;  Wang, Xue-Quan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(820Kb)  |  收藏  |  浏览/下载:247/46  |  提交时间:2013/10/16
Hybrid Compound  Benzofuran  Imidazole  Triazole  Structure-activity Relationships  
Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 111-121
作者:  Wang, Xue-Quan;  Liu, Lan-Xiang;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Li, Liang;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(4369Kb)  |  收藏  |  浏览/下载:296/98  |  提交时间:2013/07/24
Hybrid Compound  2-benzylbenzofuran  Imidazole  Cytotoxic Activities  Structure-activity Relationships