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Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载:189/30  |  提交时间:2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
DABCO-catalyzed sp(3) C-H activation: rapid access to isoxazole or coumarin-fused 3-quaternary carbon oxindoles and isoxazole-fused pyrrolidinones 期刊论文
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 41, 页码: 5637-5645
作者:  Liu,Xiong-Li;  Jing,De-Hong;  Yao,Zhen;  Zhang,Wen-Hui;  Liu,Xiong-Wei;  Yang,Zhou-Jie;  Zhao,Zhi;  Zhou,Ying;  Li,Xiao-Nian
Adobe PDF(4853Kb)  |  收藏  |  浏览/下载:169/31  |  提交时间:2016/01/19
Isoxazole Or Coumarin-fused 3-quaternary Carbon Oxindoles  Isoxazole-fused Pyrrolidinones  C-h Activation  Antibacterial Activity  Antitumor Activity  
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen,Duozhi;  Cai,Jieyun;  Cheng,Junjun;  Jing,Chenxu;  Yin,Junlin;  Jiang,Jiandong;  Peng,Zonggen;  Hao,Xiaojiang
Adobe PDF(833Kb)  |  收藏  |  浏览/下载:219/80  |  提交时间:2016/01/19
Penicamedine A, a Highly Oxygenated Hexacyclic Indole Alkaloid from Penicillium camemberti 期刊论文
CHEMISTRY & BIODIVERSITY, 2015, 卷号: 12, 期号: 10, 页码: 1547-1553
作者:  Zhu,Hucheng;  Chen,Chunmei;  Wang,Jianping;  Li,Xiao-Nian;  Wei,Guangzheng;  Guo,Yi;  Yao,Guangmin;  Luo,Zengwei;  Zhang,Jinwen;  Xue,Yongbo;  Zhang,Yonghui
Adobe PDF(686Kb)  |  收藏  |  浏览/下载:143/54  |  提交时间:2016/01/19
Anti-hiv Activity  Cytotoxic Activity  Indole Alkaloids  Penicamedine a  Penicillium Camemberti  X-ray Crystallography  
Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp. 期刊论文
STEROIDS, 2015, 卷号: 102, 页码: 101-109
作者:  Zhao,Qin;  Wang,Gao-Qian;  Chen,Guo-Dong;  Hu,Dan;  Li,Xiao-Xia;  Guo,Liang-Dong;  Li,Yan;  Yao,Xin-Sheng;  Gao,Hao
Adobe PDF(1368Kb)  |  收藏  |  浏览/下载:183/60  |  提交时间:2016/01/19
Xylariaceae  NoduliSp.rium Sp.  Endolichenic Fungus  4-methyl-progesteroid Derivatives  
Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase 期刊论文
MICROBIAL CELL FACTORIES, 2015, 卷号: 14
作者:  Zhang,Ji;  Yan,Yi-Jun;  An,Jing;  Huang,Sheng-Xiong;  Wang,Xiang-Jing;  Xiang,Wen-Sheng
Adobe PDF(1508Kb)  |  收藏  |  浏览/下载:154/29  |  提交时间:2016/01/19
25-ethyl Ivermectin  25-methyl Ivermectin  Domain Swap  Insecticidal Activity  
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
Adobe PDF(418Kb)  |  收藏  |  浏览/下载:144/51  |  提交时间:2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Isolation, synthesis and anti-hepatitis B virus evaluation of p-hydroxyacetophenone derivatives from Artemisia capillaris 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 7, 页码: 1509-1514
作者:  Zhao, Yong;  Geng, Chang-An;  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Cao, Tuan-Wu;  He, Kang;  Wang, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
Adobe PDF(2494Kb)  |  收藏  |  浏览/下载:316/97  |  提交时间:2015/06/29
Artemisia Capillaris  P-hydroxyacetophenone Derivatives  Anti-hbv Activity  Structure-activity Relationships  
Natural products as antidepressants documented in Chinese patents from 1992 to 2013 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 2, 页码: 188-198
作者:  Sun,Chang-Li;  Geng,Chang-An;  Yin,Xiu-Juan;  Huang,Xiao-Yan;  Chen,Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
Adobe PDF(245Kb)  |  收藏  |  浏览/下载:278/78  |  提交时间:2015/06/29
Chinese Patents  Natural Products  Antidepressants  
New Meroterpenoids from the Endophytic Fungus Aspergillus flavipes AIL8 Derived from the Mangrove Plant Acanthus ilicifolius 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 1, 页码: 237-248
作者:  Bai, Zhi-Qiang;  Lin, Xiuping;  Wang, Junfeng;  Zhou, Xuefeng;  Liu, Juan;  Yang, Bin;  Yang, Xianwen;  Liao, Shengrong;  Wang, Lishu;  Liu, Yonghong;  Liu,YH (reprint author),Chinese Acad Sci,Key Lab Trop Marine Bioresources & Ecol,Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine Microbiol,South China Sea Inst Oc,Guangzhou 510301,Guangdong,Peoples R China.;  baizhiqiang10@mails.ucas.ac.cn;  xiupinglin@hotmail.com;  Junfeng1982a@163.com;  xfzhou@scsio.ac.cn;  ljuan2010@qq.com;  bingo525@163.com;  xwyang@scsio.ac.cn;  ljrss@126.com;  wls6856@163.com;  yonghongliu@scsio.ac.cn
Adobe PDF(738Kb)  |  收藏  |  浏览/下载:314/75  |  提交时间:2015/06/29
Meroterpenoid  Aspergillus Flavipes  Endophytic Fungus