Lycospidine A, a New Type of Lycopodium Alkaloid from Lycopodium complanatum
Cheng, Jin-Tang1,2; Liu, Fei1,2; Li, Xiao-Nian1; Wu, Xing-De1; Dong, Liao-Bin1,2; Peng, Li-Yan1; Huang, Sheng-Xiong1; He, Juan1; Zhao, Qin-Shi1
通讯作者He, J (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China. ; hejuan@mail.kib.ac.cn ; qinshizhao@mail.kib.ac.cn
2013-05-17
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号15期号:10页码:2438-2441
摘要Lycospidine A (1), the first example of a Lycopodium alkaloid which contains an unprecedented five-membered A ring, was Isolated from Lycopodium complanatum. The unique five-membered A ring in 1 indicates that carbons 2-5 in 1 are presumably derived from proline Instead of the lysine biosynthetically, which suggests that 1 represent a new class of Lycopodium alkaloid. In addition, the unique structural feature and biosynthetic origin of 1 shed new insight into the structural diversity of Lycopodium alkaloid analogue libraries potentially accessible by engineered biosynthesis.
关键词Inhibiting Acetylcholinesterase A-c Palhinhaea-cernua Lycoposerramine-z Huperzia-serrata Biosynthesis Casuarinoides Intermediate Pelletierine Japonicum
学科领域Chemistry, Organic
DOI10.1021/ol400907v
收录类别SCI ; IC
语种英语
WOS记录号WOS:000319720900029
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16539
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Cheng, Jin-Tang,Liu, Fei,Li, Xiao-Nian,et al. Lycospidine A, a New Type of Lycopodium Alkaloid from Lycopodium complanatum[J]. ORGANIC LETTERS,2013,15(10):2438-2441.
APA Cheng, Jin-Tang.,Liu, Fei.,Li, Xiao-Nian.,Wu, Xing-De.,Dong, Liao-Bin.,...&Zhao, Qin-Shi.(2013).Lycospidine A, a New Type of Lycopodium Alkaloid from Lycopodium complanatum.ORGANIC LETTERS,15(10),2438-2441.
MLA Cheng, Jin-Tang,et al."Lycospidine A, a New Type of Lycopodium Alkaloid from Lycopodium complanatum".ORGANIC LETTERS 15.10(2013):2438-2441.
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