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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
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cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
High-quality evergreen azalea genome reveals tandem duplication-facilitated low-altitude adaptability and floral scent evolution 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 期号: 12, 页码: 2544-2560
Authors:  Wang,Xiuyun;  Gao,Yuan;  Wu,Xiaopei;  Wen,Xiaohui;  Li,Danqing;  Zhou,Hong;  Li,Zheng;  Liu,Bing;  Wei,Jianfen;  Chen,Fei;  Chen,Feng;  Zhang,Chengjun;  Zhang,Liangsheng;  Xia,Yiping
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Azalea  Rhododendron ovatum  altitude  adaptability  floral scent  terpene synthase (TPS)  tandem duplication  defence response  PHYLOGENETIC ANALYSIS  TERPENE SYNTHASES  PLANT VOLATILES  SALICYLIC-ACID  JASMONIC ACID  WHOLE-GENOME  GENE  DIVERSITY  TOOL  TRANSCRIPTOME  
New Genes Interacted With Recent Whole-Genome Duplicates in the Fast Stem Growth of Bamboos 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2021, 卷号: 38, 期号: 12, 页码: 5752-5768
Authors:  Jin,Guihua;  Ma,Peng-Fei;  Wu,Xiaopei;  Gu,Lianfeng;  Long,Manyuan;  Zhang,Chengjun;  Li,De-Zhu
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fast stem growth  orphan genes  de novo genes  WGD  woody bamboos  evolutionary innovation  EVOLUTIONARY ORIGIN  DROSOPHILA-MELANOGASTER  PHYLOGENETIC ANALYSIS  VERTEBRATE EVOLUTION  RAPID EVOLUTION  HUMAN TISSUE  YOUNG GENES  TRANSCRIPTION  EXPRESSION  HOURGLASS  
The Rhododendron Plant Genome Database (RPGD): a comprehensive online omics database for Rhododendron 期刊论文
BMC GENOMICS, 2021, 卷号: 22, 期号: 1, 页码: 376
Authors:  Liu,Ningyawen;  Zhang,Lu;  Zhou,Yanli;  Tu,Mengling;  Wu,Zhenzhen;  Gui,Daping;  Ma,Yongpeng;  Wang,Jihua;  Zhang,Chengjun
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Rhododendron  Horticulture plant  Database  Functional genomics  COMPLETE CHLOROPLAST GENOME  ERICACEAE  YUNNAN  DNA  
Genetic innovations: Transposable element recruitment and de novo formation lead to the birth of orphan genes in the rice genome 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2021, 卷号: 59, 期号: 2, 页码: 341-351
Authors:  Jin,Gui-Hua;  Zhou,Yan-Li;  Yang,Hong;  Hu,Yan-Ting;  Shi,Yong;  Li,Ling;  Siddique,Abu N.;  Liu,Chang-Ning;  Zhu,An-Dan;  Zhang,Cheng-Jun;  Li,De-Zhu
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comparative genomics  origin  orphan gene  transposable element  LINEAGE-SPECIFIC GENES  EVOLUTION  ORIGIN  IDENTIFICATION  EMERGENCE  PROTEIN  DUPLICATION  ALIGNMENT  SETS  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
Authors:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
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Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
Authors:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD(+) levels 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 卷号: 64, 期号: 11, 页码: 1929-1948
Authors:  Fang,Chengchi;  Gan,Xiaoni;  Zhang,Chengjun;  He,Shunping
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new chimeric genes  essential function  NAD plus rate-limiting enzyme  coevolution  COLONY-ENHANCING FACTOR  DE-NOVO ORIGINATION  PHYLOGENETIC ANALYSIS  PROTEIN DIVERSITY  RAPID EVOLUTION  DUPLICATE GENES  GENERATION TIME  PATHWAY  YOUNG  NEOFUNCTIONALIZATION  
Synthesis, antitumor activity, and molecular docking of (-)-epigallocatechin-3-gallate-4 beta-triazolopodophyllotoxin conjugates 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 卷号: 23, 期号: 8, 页码: 772-780
Authors:  Zi,Cheng-Ting;  Yang,Liu;  Hu,Yue;  Zhang,Pan;  Tang,Han;  Zhang,Bang-Lei;  Shen,Xiao-Jing;  Kong,Qing-Hua;  Wang,Ya;  Wang,Xuan-Jun;  Sheng,Jun
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Podophyllotixin  EGCG  click reaction  antitumor activity  molecular docking  PODOPHYLLOTOXIN  DERIVATIVES  CONGENERS  
The complete chloroplast genome of Actinidia rubus (Actinidiaceae) 期刊论文
MITOCHONDRIAL DNA PART B-RESOURCES, 2020, 卷号: 5, 期号: 1, 页码: 366-367
Authors:  Xu, Yu-Sheng;  Zhang, Cheng-Gui;  Chen, Jun-Tong;  Li, Li-Juan;  Liao, Chuan-Jiang;  Lv, Zhen-Yu;  Jiang, Zhi-Lin
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Actinidia rubus  chloroplast genome  phylogenetic analysis