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Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：232/50  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
浏览  |  Adobe PDF(3282Kb)  |  收藏  |  浏览/下载：340/74  |  提交时间：2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
浏览  |  Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：713/115  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(1677Kb)  |  收藏  |  浏览/下载：2889/266  |  提交时间：2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles  
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells 期刊论文
CANCER LETTERS, 2009, 卷号: 275, 期号: 2, 页码: 247-255
作者:  Sun, Wei-Hao;  Chen, Guo-Sheng;  Ou, Xi-Long;  Yang, Ye;  Luo, Cheng;  Zhang, Yuan;  Shao, Yun;  Xu, Hai-Chen;  Xiao, Bin;  Xue, Yi-Ping;  Zhou, Su-Ming;  Zhao, Qin-Shi;  Ding, Guo-Xian
Adobe PDF(635Kb)  |  收藏  |  浏览/下载：1292/378  |  提交时间：2011/12/19
Pancreatic Cancer  Cyclooxygenase-2  Peroxisome Proliferators-activated Receptor  Gamma  Proliferation  Apoptosis  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载：372/109  |  提交时间：2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis