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Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways 期刊论文
FRONTIERS IN ONCOLOGY, 2020
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
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Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 13, 期号: 3, 页码: 1672-1680
作者:  Yuan,Yan;  Du,Yong;  Hu,Xiao-Ye;  Liu,Mei-Yuan;  Du,Ji-Ke;  Liu,Xue-Min;  Yu,Hong-En;  Wang,Tian-Zhu;  Pu,Jian-Xin;  Zhong,Qian;  Zou,Qing-Feng
浏览  |  Adobe PDF(1897Kb)  |  收藏  |  浏览/下载：279/40  |  提交时间：2017/10/23
Side Population  C-myc  Cancer  Expression  Radioresistance  Identification  Subpopulation  Combination  Pathway  Domain  Longikaurin a  Nasopharyngeal Carcinoma  Cancer Stem Cells  
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008
作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian;  Liu, Xiaolan;  Yang, Lifang;  Peng, Songling;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya;  Liu,JK (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Beijing 100864,Yunnan,Peoples R China.;  jkliu@mail.kib.ac.cn;  ycao98@vip.sina.com
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Necoalbaconol  Necroptosis  Ripk  Tnf Alpha  Nf-kappa b Signaling Pathway  Ros  
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
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Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
The anticancer effect and mechanism of alpha-hederin on breast cancer cells 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 卷号: 45, 期号: 2, 页码: 757-763
作者:  Cheng, Lin;  Xia, Tian-Song;  Wang, Yi-Fen;  Zhou, Wenbin;  Liang, Xiu-Qing;  Xue, Jin-Qiu;  Shi, Liang;  Wang, Ying;  Ding, Qiang;  Wang, Minhai;  Ding, Q (reprint author), Nanjing Med Univ, Affiliated Hosp 1, Jiangsu Breast Dis Ctr, 300 Guangzhou Rd, Nanjing 210029, Jiangsu, Peoples R China.
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Alpha-hederin  Breast Cancer  Apoptosis  Mechanism  Mitochondria  
PEROXIREDOXIN 1 (PRDX1) AS A RADIO-SENSITIZATION TARGET IN GROUP 3 MEDULLOBLASTOMAS 期刊论文
NEURO-ONCOLOGY, 2014, 卷号: 16, 期号: 1, 页码: 89-89
作者:  Li, Lin;  Wang, Wei-Guang;  Pu, Jian-Xin;  Sun, Han-Dong;  Remke, Marc;  Taylor, Michael D.;  Ruggieri, Rosamaria;  Symons, Marc H.;  Vanan, Magimairajan Issai
收藏  |  浏览/下载：222/0  |  提交时间：2014/07/28
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
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Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent  
Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer 期刊论文
BREAST CANCER RESEARCH, 2014, 卷号: 16, 期号: 4, 页码: 8220-8224
作者:  O'Leary, Patrick C.;  Terrile, Marta;  Bajor, Malgorzata;  Gaj, Pawel;  Hennessy, Bryan T.;  Mills, Gordon B.;  Zagozdzon, Agnieszka;  O'Connor, Darran P.;  Brennan, Donal J.;  Connor, Kate;  Li, Jane;  Gonzalez-Angulo, Ana Maria;  Sun, Han-Dong;  Pu, Jian-Xin;  Ponten, Fredrik;  Uhlen, Mathias;  Jirstrom, Karin;  Nowis, Dominika A.;  Crown, John P.;  Zagozdzon, Radoslaw;  Gallagher, William M.;  Zagozdzon,R (reprint author),UCD Sch Biomol & Biomed Sci,UCD Conway Inst,Canc Biol & Therapeut Lab,Dublin 4,Ireland.;  radoslaw.zagozdzon@wum.edu.pl;  william.gallagher@ucd.ie
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Natural-products  Roots  Secretion  Norsesquiterpenoids  Norbisabolane  Pyrimidine  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：665/101  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(1677Kb)  |  收藏  |  浏览/下载：2562/230  |  提交时间：2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles