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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：340/77  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
作者:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
浏览  |  Adobe PDF(7649Kb)  |  收藏  |  浏览/下载：204/26  |  提交时间：2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
The Therapeutic Effects of Longikaurin A, a Natural ent-Kauranoid, in Esophageal Squamous Cell Carcinoma Depend on ROS Accumulation and JNK/p38 MAPK Activation 期刊论文
Toxicology Letters, 2017, 卷号: 280, 页码: 106–115
作者:  Yun Chea;  Jingnan Wang;  Zuyang Yuan;  Yuan Li;   Zhiliang Lu;  Zhirong Zhang;  Jinyao Zhang;  Jun Wan;  Handong Sun;  Zhaoli Chen;  Jianxin Pu;  Jie He
浏览  |  Adobe PDF(1858Kb)  |  收藏  |  浏览/下载：230/42  |  提交时间：2017/11/20
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 13, 期号: 3, 页码: 1672-1680
作者:  Yuan,Yan;  Du,Yong;  Hu,Xiao-Ye;  Liu,Mei-Yuan;  Du,Ji-Ke;  Liu,Xue-Min;  Yu,Hong-En;  Wang,Tian-Zhu;  Pu,Jian-Xin;  Zhong,Qian;  Zou,Qing-Feng
浏览  |  Adobe PDF(1897Kb)  |  收藏  |  浏览/下载：379/48  |  提交时间：2017/10/23
Side Population  C-myc  Cancer  Expression  Radioresistance  Identification  Subpopulation  Combination  Pathway  Domain  Longikaurin a  Nasopharyngeal Carcinoma  Cancer Stem Cells  
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
浏览  |  Adobe PDF(2162Kb)  |  收藏  |  浏览/下载：309/68  |  提交时间：2016/01/19
Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1137, e1137
作者:  Liao, Y-J;  Bai, H-Y;  Li, Z-H;  Zou, J.;  Chen, J-W;  Zheng, F.;  Zhang, J-X;  Mai, S-J;  Zeng, M-S;  Sun, H-D;  Pu, J-X;  Xie, D.
浏览  |  Adobe PDF(5082Kb)  |  收藏  |  浏览/下载：607/57  |  提交时间：2014/05/16
Longikaurin a  Hepatocellular Carcinoma  Cell Cycle Arrest  Apoptosis  Skp2  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载：371/109  |  提交时间：2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis