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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载:312/1  |  提交时间:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载:214/1  |  提交时间:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:315/1  |  提交时间:2017/07/24
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载:134/1  |  提交时间:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
The re‑emergence of natural products for drug discovery in the genomics era 期刊论文
Nature Reviews Drug Discovery, 2015, 页码: nrd4510
作者:  Alan L. Harvey
Adobe PDF(540Kb)  |  收藏  |  浏览/下载:97/0  |  提交时间:2017/08/22
Antichlamydial Sterol from the Red Sea Sponge Callyspongia aff. implexa 期刊论文
planta medica, 2015, 页码: 1
作者:  Usama Ramadan Abdelmohsen
Adobe PDF(196Kb)  |  收藏  |  浏览/下载:68/0  |  提交时间:2017/08/23
Can we safely target the WNT pathway? 期刊论文
NATURE REVIEWS DRUG DISCOVERY, 2014, 卷号: 13, 页码: 513
作者:  Michael Kahn
Adobe PDF(1565Kb)  |  收藏  |  浏览/下载:73/0  |  提交时间:2017/08/18
Reducing effect of an extract of Phaseolus vulgaris on food intakein mice — Focus on highly palatable foods 期刊论文
Fitoterapia, 2013, 卷号: 85, 期号: 0, 页码: 14-19
作者:  Barbara Loi;  Noemi Fantini;  Giancarlo Colombo;  Gian Luigi Gessa;  Antonella Riva;  Ezio Bombardelli;  Paolo Morazzoni;  Mauro A.M. Carai
Adobe PDF(507Kb)  |  收藏  |  浏览/下载:50/1  |  提交时间:2017/07/21
WNT signalling pathways astherapeutic targets in cancer 期刊论文
NATURE REVIEWS CANCER, 2013, 卷号: 13, 期号: 0, 页码: 11—26
作者:  Jamie N. Anastas;  Randall T. Moon
Adobe PDF(498Kb)  |  收藏  |  浏览/下载:72/1  |  提交时间:2017/07/21
Therapeutic Targeting of Autophagy in Disease:Biology and Pharmacology 期刊论文
Pharmacol Rev, 2013, 卷号: 65, 期号: 0, 页码: 1162–1197
作者:  Yan Cheng;  Xingcong Ren;  William N. Hait;  Jin-Ming Yang
Adobe PDF(1425Kb)  |  收藏  |  浏览/下载:43/1  |  提交时间:2017/07/24