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The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 191, 页码: 11
Authors:  Xu, Guowei;  Yang, Yaqing;  Yang, Yanming;  Song, Gao;  Li, Shanshan;  Zhang, Jiajun;  Yang, Weimin;  Wang, Liang-Liang;  Weng, Zhiying;  Zuo, Zhili
Favorite  |  View/Download：11/0  |  Submit date：2020/05/27
Adenylate cyclase  Agonist  Virtual screening  Cyclic adenosine monophosphate  Interleukin-6  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
Authors:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
Favorite  |  View/Download：16/0  |  Submit date：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
The amazing potential of fungi: 50 ways we can exploit fungi industrially 期刊论文
FUNGAL DIVERSITY, 2019, 卷号: 97, 期号: 1, 页码: 1-136
Authors:  Hyde, Kevin D.;  Xu, Jianchu;  Rapior, Sylvie;  Jeewon, Rajesh;  Lumyong, Saisamorn;  Niego, Allen Grace T.;  Abeywickrama, Pranami D.;  Aluthmuhandiram, Janith V. S.;  Brahamanage, Rashika S.;  Brooks, Siraprapa;  Chaiyasen, Amornrat;  Chethana, K. W. Thilini;  Chomnunti, Putarak;  Chepkirui, Clara;  Chuankid, Boontiya;  de Silva, Nimali I.;  Doilom, Mingkwan;  Faulds, Craig;  Gentekaki, Eleni;  Gopalan, Venkat;  Kakumyan, Pattana;  Harishchandra, Dulanjalee;  Hemachandran, Hridya;  Hongsanan, Sinang;  Karunarathna, Anuruddha;  Karunarathna, Samantha C.;  Khan, Sehroon;  Kumla, Jaturong;  Jayawardena, Ruvishika S.;  Liu, Jian-Kui;  Liu, Ningguo;  Luangharn, Thatsanee;  Macabeo, Allan Patrick G.;  Marasinghe, Diana S.;  Meeks, Dan;  Mortimer, Peter E.;  Mueller, Peter;  Nadir, Sadia;  Nataraja, Karaba N.;  Nontachaiyapoom, Sureeporn;  O'Brien, Meghan;  Penkhrue, Watsana;  Phukhamsakda, Chayanard;  Ramanan, Uma Shaanker;  Rathnayaka, Achala R.;  Sadaba, Resurreccion B.;  Sandargo, Birthe;  Samarakoon, Binu C.;  Tennakoon, Danushka S.;  Siva, Ramamoorthy;  Sriprom, Wasan;  Suryanarayanan, T. S.;  Sujarit, Kanaporn;  Suwannarach, Nakarin;  Suwunwong, Thitipone;  Thongbai, Benjarong;  Thongklang, Naritsada;  Wei, Deping;  Wijesinghe, S. Nuwanthika;  Winiski, Jake;  Yan, Jiye;  Yasanthika, Erandi;  Stadler, Marc
View  |  Adobe PDF(12864Kb)  |  Favorite  |  View/Download：26/4  |  Submit date：2019/10/28
Biocontrol  Biodiversity  Biotechnology  Food  Fungi  Mushrooms  
Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
Authors:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
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Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
Authors:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
View  |  Adobe PDF(854Kb)  |  Favorite  |  View/Download：178/17  |  Submit date：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
托品烷、芦竹碱和百里酚衍生物的合成及生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  尹秀娟
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九株链霉菌的次级代谢产物及其生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  杨瑞敏
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一种降齐墩果酸化合物抑制脂肪细胞分化和调节脂代谢的机理初探 学位论文
: 中国科学院大学, 2017
Authors:  彭莉
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Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
Authors:  Hu, Rongkuan;  Yan, Huan;  Fei, Xiaoyan;  Liu, Haiyang;  Wu, Jiarui
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(+/-)-Uncarilins A and B, Dimeric Isoechinulin-Type Alkaloids from Uncaria rhynchophylla 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 4, 页码: 959-964
Authors:  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Hou, Bo;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
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