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Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 2411
作者:  Zhao, Zhuohui;  Deng, Zhen-Tao;  Huang, Suling;  Ning, Mengmeng;  Feng, Ying;  Shen, Yu;  Zhao, Qin-Shi;  Leng, Ying
浏览  |  Adobe PDF(6451Kb)  |  收藏  |  浏览/下载:14/6  |  提交时间:2024/04/30
Alisol B  non-alcoholic steatohepatitis  RAR alpha  CD36  FATTY LIVER  HEPATIC STEATOSIS  RECEPTOR  ORIENTALE  LIPOPROTEINS  23-ACETATE  AGONIST  CD36  
An Approach for the Synthesis of Pyrazolo[1,5-a]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 18, 页码: 12762-12771
作者:  Ren,Jian;  Ding,Shihua;  Li,Xiaonian;  Bi,Ran;  Zhao,Qinshi
浏览  |  Adobe PDF(1469Kb)  |  收藏  |  浏览/下载:80/18  |  提交时间:2022/04/02
BIOLOGICAL EVALUATION  REGIOSELECTIVE SYNTHESIS  CASCADE REACTIONS  FUNCTIONALIZATION  DEHYDROGENATION  DISCOVERY  POTENT  BOND  SAR  
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu;  Zhao, Qin-shi;  Leng, Ying
浏览  |  Adobe PDF(3899Kb)  |  收藏  |  浏览/下载:106/29  |  提交时间:2021/01/05
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:375/42  |  提交时间:2017/12/18
Sesquiterpenoids from Tussilago farfara and Their Inhibitory Effects on Nitric Oxide Production 期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 8-9, 页码: 703-709
作者:  Qin, Zhi-Bin;  Zhang, Jing;  Wu, Xing-De;  He, Juan;  Ding, Lin-Fen;  Peng, Li-Yan;  Li, Xing-Yao;  Li, Yan;  Deng, Liang;  Guo, Ya-Dong;  Zhao, Qin-Shi;  Schoch, CL (reprint author), Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA.;  schoch2@ncbi.nlm.nih.gov
Adobe PDF(166Kb)  |  收藏  |  浏览/下载:265/80  |  提交时间:2014/10/11
Tussilago Farfara  Asteraceae  Sesquiterpenoid  Nitric Oxide Inhibition  
The Relationships between Chemical and Genetic Differentiation and Environmental Factors across the Distribution of Erigeron breviscapus (Asteraceae) 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11, 页码: e74490
作者:  Li, Xiang;  Peng, Li-yan;  Zhang, Shu-dong;  Zhao, Qin-shi;  Yi, Ting-shuang
Adobe PDF(516Kb)  |  收藏  |  浏览/下载:283/53  |  提交时间:2014/01/13
Temperature Stress  Aflp  Plant  Acid  Inhibition  Flavonoids  Diversity  Lactuceae  Extract  
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells 期刊论文
CANCER LETTERS, 2009, 卷号: 275, 期号: 2, 页码: 247-255
作者:  Sun, Wei-Hao;  Chen, Guo-Sheng;  Ou, Xi-Long;  Yang, Ye;  Luo, Cheng;  Zhang, Yuan;  Shao, Yun;  Xu, Hai-Chen;  Xiao, Bin;  Xue, Yi-Ping;  Zhou, Su-Ming;  Zhao, Qin-Shi;  Ding, Guo-Xian
Adobe PDF(635Kb)  |  收藏  |  浏览/下载:1251/366  |  提交时间:2011/12/19
Pancreatic Cancer  Cyclooxygenase-2  Peroxisome Proliferators-activated Receptor  Gamma  Proliferation  Apoptosis  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载:343/103  |  提交时间:2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis