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KIB OpenIR
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Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity 期刊论文
NATURAL PRODUCT RESEARCH, 2023
作者:  Zhang,Hong;  Fang,Wen-Tao;  Li,Yan;  Kong,Qing-Hua;  Fang,Cheng-Wu;  Luo,Han;  Liu,Shou-Jin
浏览  |  Adobe PDF(1116Kb)  |  收藏  |  浏览/下载：33/12  |  提交时间：2024/07/30
Rubiaceae  Rubia cordifolia L  naphthoquinone derivative  flavonoids  NO inhibitory activity  NAPHTHOHYDROQUINONE DIMERS  SECONDARY METABOLITES  IDENTIFICATION  ANTHRAQUINONES  PURIFICATION  DERIVATIVES  FLAVONOIDS  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：19/8  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Uncovering the role of a positive selection site of wax ester synthase/diacylglycerol acyltransferase in two closely related Stipa species in wax ester synthesis under drought stress 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2020
作者:  Yang, Yunqiang;  Zhou, Zhili;  Li, Yan;  Lv, Yanqiu;  Yang, Danni;  Yang, Shihai;  Wu, Jianshuang;  Li, Xiong;  Gu, Zhijia;  Sun, Xudong;  Yang, Yongping
浏览  |  Adobe PDF(3551Kb)  |  收藏  |  浏览/下载：264/68  |  提交时间：2021/01/05
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：189/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：302/72  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis and antitumor activity of aza-brazilan derivatives containing imidazolium salt pharmacophores 期刊论文
MEDCHEMCOMM, 2019, 卷号: 10, 期号: 6, 页码: 1027-1036
作者:  Huang, Mingqin;  Duan, Shengzu;  Ma, Xueqiong;  Cai, Bicheng;  Wu, Dongmei;  Li, Yan;  Li, Liang;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(3833Kb)  |  收藏  |  浏览/下载：203/36  |  提交时间：2019/07/29
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：321/45  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载：498/217  |  提交时间：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载：158/0  |  提交时间：2019/03/29
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 152, 页码: 105-112
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载：314/0  |  提交时间：2018/12/27