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Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：219/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 10
作者:  Jiang,Shiyou;  Du,Jiacheng;  Kong,Qinghua;  Li,Chaocui;  Li,Yan;  Sun,Handong;  Pu,Jianxin;  Mao,Bingyu
Adobe PDF(7288Kb)  |  收藏  |  浏览/下载：199/54  |  提交时间：2016/01/19
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
Adobe PDF(1121Kb)  |  收藏  |  浏览/下载：460/58  |  提交时间：2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin  
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 卷号: 11, 期号: 1, 页码: 200
作者:  Zou, Qing-Feng;  Du, Ji-Ke;  Zhang, Hua;  Wang, Hong-Bo;  Hu, Ze-Dong;  Chen, Shu-Peng;  Du, Yong;  Li, Man-Zhi;  Xie, Dan;  Zou, Juan;  Sun, Han-Dong;  Pu, Jian-Xin;  Zeng, Mu-Sheng
Adobe PDF(3788Kb)  |  收藏  |  浏览/下载：285/42  |  提交时间：2013/10/16
Longikaurin a (Lk-a)  Apoptosis  Caspase  Nasopharyngeal Carcinoma  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：668/197  |  提交时间：2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh  
Pharicin A, a novel natural ent-kaurene diterpenoid, induces mitotic arrest and mitotic catastrophe of cancer cells by interfering with BubR1 function 期刊论文
CELL CYCLE, 2010, 卷号: 9, 期号: 14, 页码: 2897-2907
作者:  Xu, Han-Zhang;  Huang, Ying;  Wu, Ying-Li;  Zhao, Yong;  Xiao, Wei-Lie;  Lin, Qi-Shan;  Sun, Han-Dong;  Dai, Wei;  Chen, Guo-Qiang
Adobe PDF(3997Kb)  |  收藏  |  浏览/下载：126/35  |  提交时间：2015/08/17
Pharicin a  Mitotic Arrest  Leukemia  Tumor Cells  Spindle Checkpoint