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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载:299/1  |  提交时间:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载:204/1  |  提交时间:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:309/1  |  提交时间:2017/07/24
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载:329/1  |  提交时间:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
WNT signalling pathways astherapeutic targets in cancer 期刊论文
NATURE REVIEWS CANCER, 2013, 卷号: 13, 期号: 0, 页码: 11—26
作者:  Jamie N. Anastas;  Randall T. Moon
Adobe PDF(498Kb)  |  收藏  |  浏览/下载:67/1  |  提交时间:2017/07/21
Quantum dots (QDs) restrain human cervicalcarcinoma HeLa cell proliferation through inhibitionof the ROCK-c-Myc signaling 期刊论文
Integr. Biol., 2013, 卷号: 5, 期号: 0, 页码: 590--596
作者:  Liqun Chen;  Guangbo Qu;  Changwen Zhang;  Shuping Zhang;  iuyang He;  Nan Sang;  Sijin Liu
Adobe PDF(3624Kb)  |  收藏  |  浏览/下载:44/1  |  提交时间:2017/07/24
Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-kB 期刊论文
J Ginseng Res, 2013, 卷号: 37, 期号: 1, 页码: 74-79
作者:  Chun Liang;  Yan Ding;  Seok Bean Song;  Jeong Ah Kim;  Nguyen Manh Cuong;  Jin Yeul Ma;  Young Ho Kim
Adobe PDF(19873Kb)  |  收藏  |  浏览/下载:68/1  |  提交时间:2017/07/24
Panax Ginseng  Panax Stipuleanatus  Oleanane-type Triterpenoid  Nuclear Factor-κb  
Therapeutic Targeting of Autophagy in Disease:Biology and Pharmacology 期刊论文
Pharmacol Rev, 2013, 卷号: 65, 期号: 0, 页码: 1162–1197
作者:  Yan Cheng;  Xingcong Ren;  William N. Hait;  Jin-Ming Yang
Adobe PDF(1425Kb)  |  收藏  |  浏览/下载:42/1  |  提交时间:2017/07/24
A ring-distortion strategy to constructstereochemically complex and structurally diversecompounds from natural products 期刊论文
NATURE CHEMISTRY, 2013, 卷号: 5, 期号: 0, 页码: 195-202
作者:  Robert W. Huigens III;  Karen C. Morrison;  Robert W. Hicklin;  Timothy A. Flood Jr, Michelle F. Richter;  Paul J. Hergenrother
Adobe PDF(512Kb)  |  收藏  |  浏览/下载:89/1  |  提交时间:2017/07/24
Cytotoxic Cycloartane Triterpenes of the TraditionalChinese Medicine “Shengma” (Cimicifuga dahurica) 期刊论文
Planta Med, 2013, 卷号: 79, 期号: 0, 页码: 60–69
作者:  Yin Nian;  Hai-YanWang;  Lin Zhou;  Jia Su;  Yan Li;  Ming-Hua Qiu
Adobe PDF(185Kb)  |  收藏  |  浏览/下载:70/1  |  提交时间:2017/07/24
Ranunculaceae  Cimicifuga Dahurica  Cycloartane Triterpenes  Cytotoxicity  Structure‑activity Relationships