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Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：68/9  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production 期刊论文
MOLECULAR CARCINOGENESIS, 2017, 卷号: 56, 期号: 5, 页码: 1414-1426
作者:  Yu, Xinfang;  Li, Wei;  Deng, Qipan;  You, Shuo;  Liu, Haidan;  Peng, Songling;  Liu, Xiaolan;  Lu, Jingchen;  Luo, Xiangjian;  Yang, Lifang;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Liu, Wenbin;  Wu, Shengqi;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
Adobe PDF(6365Kb)  |  收藏  |  浏览/下载：316/102  |  提交时间：2017/06/30
Angiogenesis  Breast Cancer  Egfr  Neoalbaconol  Vegf  
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：202/54  |  提交时间：2017/11/20
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review) 期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 2, 页码: 547-554
作者:  Luo, Xiangjian;  Yu, Xinfang;  Liu, Sufang;  Deng, Qipan;  Liu, Xiaolan;  Peng, Songling;  Li, Hongde;  Liu, Jikai;  Cao, Ya
Adobe PDF(755Kb)  |  收藏  |  浏览/下载：339/168  |  提交时间：2015/12/17
Natural Products  Grifolin  Neoalbaconol  Epigallocatechin-3-gallate  Cancer Prevention  
Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 267, 期号: 1, 页码: 95-103
作者:  Fang, Xian-Ying;  Chen, Wei;  Fan, Jun-Ting;  Song, Ran;  Wang, Lu;  Gu, Yan-Hong;  Zeng, Guang-Zhi;  Shen, Yan;  Wu, Xue-Feng;  Tan, Ning-Hua;  Xu, Qiang;  Sun, Yang
Adobe PDF(1855Kb)  |  收藏  |  浏览/下载：741/127  |  提交时间：2013/03/18
Ra-v  Cyclopeptide  Mitochondrial Apoptosis Pathway  Pi3k/akt  Breast Cancer  
Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 7, 页码: 1883-1898
作者:  Yue, Grace G. L.;  Fan, Jun-Ting;  Lee, Julia K. M.;  Zeng, Guang-Zhi;  Ho, Tina W. F.;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
Adobe PDF(2713Kb)  |  收藏  |  浏览/下载：405/79  |  提交时间：2012/07/25
Cyclopeptide  Ra-v  Angiogenesis  Erk1  2  Rubia Yunnanensis  Huvec  Hmec-1  Endothelial Cells