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Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:  Li, Tian-Ze;  Huang, Xiao-Yan;  Sun, Jin-Jin;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1234Kb)  |  收藏  |  浏览/下载：43/10  |  提交时间：2024/04/30
(+)-Paeoveitol derivatives  Antidepressant  Forced swimming test  Monoamine neurotransmitter  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：79/15  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3731Kb)  |  收藏  |  浏览/下载：220/49  |  提交时间：2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：239/76  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Dereplication-guided isolation of a new indole alkaloid triglycoside from the hooks of Uncaria rhynchophylla by LC with ion trap time-of-flight MS 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2018, 卷号: 41, 期号: 7, 页码: 1532-1538
作者:  Zhang, Jian-Gang;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(1155Kb)  |  收藏  |  浏览/下载：244/72  |  提交时间：2018/05/08
5-hydroxytryptamine Receptors  Dereplication-guided Isolation  Indole Alkaloid Triglycoside  Melatonin Receptors  Traditional Chinese Medicine  
Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：278/99  |  提交时间：2017/10/23
Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载：352/64  |  提交时间：2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships  
Lignans from the Fruits of Melia toosendan and Their Agonistic Activities on Melatonin Receptor MT1 期刊论文
PLANTA MEDICA, 2015, 卷号: 81, 期号: 10, 页码: 847-854
作者:  Wang, Hao;  Geng, Chang-An;  Xu, Hong-Bo;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Yang, Cai-Yan;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(244Kb)  |  收藏  |  浏览/下载：272/98  |  提交时间：2015/12/17
Melia Toosendan  Meliaceae  Lignans  Mt1 Receptor  Agonistic Activity