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Alkaloids from Tabernaemontana divaricata combined with fluconazole to overcome fluconazole resistance in Candida albicans 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104515
作者:  Zhang,Yu;  Bai,Xue;  Yuwen,Huan-Sha;  Guo,Ling-Li;  Liu,Jian-Wen;  Hao,Xiao-Jiang
Adobe PDF(1576Kb)  |  收藏  |  浏览/下载：127/51  |  提交时间：2022/04/02
Tabernaemontana divaricate  Taberdines A-K  Reversal of fluconazole resistance  Candida albicans  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：87/17  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
作者:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(2463Kb)  |  收藏  |  浏览/下载：113/33  |  提交时间：2022/04/02
Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS  
Cytotoxic sesquiterpenoids against hepatic stellate cell line LX2 from Artemisia lavandulaefolia 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Shen, Cheng;  Huang, Xiao-Yan;  Geng, Chang-An;  Li, Tian-Ze;  Wang, Jin-Ping;  Tang, Shuang;  Su, Li-Hua;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2199Kb)  |  收藏  |  浏览/下载：175/40  |  提交时间：2021/01/05
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Liu, Hui;  He, Xiao-Zhi;  Feng, Mi-Yan;  Yuan-Zeng;  Rauwolf, Tyler J.;  Shao, Li-Dong;  Ni, Wei;  Yan, Hui;  Porco, John A., Jr.;  Hao, Xiao-Jiang;  Qin, Xu-Jie;  Liu, Hai-Yang
浏览  |  Adobe PDF(3924Kb)  |  收藏  |  浏览/下载：240/77  |  提交时间：2021/01/05
Nonpeptidal compounds from the insect Polyphaga plancyi and their biological evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Zhu, Hong-Jie;  Xu, Te;  Yan, Yong-Ming;  Cheng, Yong-Xian
浏览  |  Adobe PDF(1777Kb)  |  收藏  |  浏览/下载：105/31  |  提交时间：2021/01/05
Skeletal meroterpenoids from Ganoderma petchii mushrooms that potentially stimulate umbilical cord mesenchymal stem cells 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Dai, Wei-Feng;  Zhu, Yan-Xia;  Qin, Fu-Ying;  Chang, Jun-Lei;  Zeng, Yue;  Wang, Ji-Gang;  Zhang, Yuan-Yuan;  Cheng, Yong-Xian
浏览  |  Adobe PDF(5679Kb)  |  收藏  |  浏览/下载：147/28  |  提交时间：2021/01/05
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：217/35  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine