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Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
作者:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(2611Kb)  |  收藏  |  浏览/下载：200/84  |  提交时间：2022/04/02
Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
Novel cytotoxic benzophenones from Garcinia paucinervis identified by UPLC-QTOF-MSE 期刊论文
PLANTA MEDICA, 2016, 卷号: 82, 页码: 1
作者:  Li, P.;  Senthilkumar, H. Anandhi;  Figueroa, M.;  Wu, S. B.;  Fata, J. E.;  Kennelly, E. J.;  Long, C.
浏览  |  Adobe PDF(138Kb)  |  收藏  |  浏览/下载：249/79  |  提交时间：2017/12/11
Uplc-qtof-mse  Novel Benzophenones  Garcinia Paucinervis  Cytotoxicity  Breast Cancer Cell Lines  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity 期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2011, 卷号: 34, 期号: 12, 页码: 2007-2014
作者:  Zhao, Wei;  Pu, Jian Xin;  Du, Xue;  Wu, Ying Li;  Zhao, Yong;  He, Fei;  Zhang, Hai Bo;  Xue, Yong Bo;  Xiao, Wei Lie;  Chen, Guo Qiang;  Sun, Han Dong
Adobe PDF(682Kb)  |  收藏  |  浏览/下载：353/113  |  提交时间：2012/04/10
Neolignan  Triterpenoid  Diterpenoid  Isodon Coetsa  Cytotoxicity  Human Tumor Cell Lines  
Prediction of broad spectrum resistance of tumors towards anticancer drugs 期刊论文
CLINICAL CANCER RESEARCH, 2008, 卷号: 14, 期号: 8, 页码: 2405-2412
Efferth, Thomas; Konkimalla, V. Badireenath; Wang, Yi-Fen; Sauerbrey, Axel; Meinhardt, Silke; Zintl, Felix; Mattern, Juegen; Volm, Manfred
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Traditional Chinese Medicine  Cassette Transporter Genes  Short-term Test  Multidrug-resistance  Cell-lines  Cancer-chemotherapy  Tetrazolium Assay  Sensitivity  Leukemia  Cytotoxicity  
Cytotoxic and new tetralone derivatives from Berchemia floribunda (WALL.) BRONGN. 期刊论文
CHEMISTRY & BIODIVERSITY, 2006, 卷号: 3, 期号: 6, 页码: 646-653
作者:  Wang, Yi-Fen;  Cao, Jian-Xin;  Efferth, Thomas;  Lai, Gou-Fang;  Luo, Shi-De
Adobe PDF(99Kb)  |  收藏  |  浏览/下载：392/194  |  提交时间：2011/11/24
Juglans-mandshurica  Cell Lines  Flavonoids  Artesunate  
New glycosides from Tetracentron sinense and their cytotoxic activity 期刊论文
CHEMISTRY & BIODIVERSITY, 2006, 卷号: 3, 期号: 9, 页码: 1023-1030
作者:  Wang, Yi-Fen;  Lai, Gou-Fang;  Efferth, Thomas;  Cao, Jian-Xin;  Luo, Shi-De
Adobe PDF(506Kb)  |  收藏  |  浏览/下载：240/79  |  提交时间：2011/11/24
Multidrug-resistance  Cell Lines  Transporter  Artesunate  Glucosides  Triterpene  Bark  
Natural aromatic steroids as potential molecular fossils from the fruiting bodies of the ascomycete Daldinia concentrica 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2004, 卷号: 67, 期号: 12, 页码: 2133-2135
作者:  Qin, XD;  Liu, JK
Adobe PDF(63Kb)  |  收藏  |  浏览/下载：302/77  |  提交时间：2012/03/21
Isoprenoid-substituted Flavonoids  Tumor-cell Lines  Root Bark  Heterophyllus Lamk  Moraceae Plants  Prenylflavones  Constituents  Communis  Altilis