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Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：50/9  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1081697
作者:  Su, Deyuan;  Gong, Ye;  Li, Songyu;  Yang, Jian;  Nian, Yin
浏览  |  Adobe PDF(3909Kb)  |  收藏  |  浏览/下载：26/5  |  提交时间：2024/08/21
Cyclovirobuxine D  Ca(v)3  2  Ca(v)2  Buxus microphylla  analgesic effects  ROOT GANGLION NEURONS  CALCIUM-CHANNELS  CELL-PROLIFERATION  PACLITAXEL  RAT  RECEPTOR  GENE  EXPRESSION  APOPTOSIS  CURRENTS  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：183/51  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Seven new veratramine-type alkaloids with potent analgesic effect from Veratrum taliense 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 7
作者:  Li, Qiong;  Zhao, Yun-Li;  Long, Cheng-Bo;  Zhu, Pei-Feng;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(829Kb)  |  收藏  |  浏览/下载：268/71  |  提交时间：2019/11/07
V. taliense  Veratrum  Liliaceae  Veratramine-type alkaloids  Analgesic activity  
An overview of grayanane diterpenoids and their biological activities from the Ericaceae family in the last seven years 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 400-416
作者:  Li, Chun-Huan;  Zhang, Jia-Yao;  Zhang, Xiu-Yun;  Li, Sheng-Hong;  Gao, Jin-Ming
浏览  |  Adobe PDF(2414Kb)  |  收藏  |  浏览/下载：310/56  |  提交时间：2019/04/15
Grayanane diterpenoids  Ericaceae  Bioactivities  Analgesic activity  Anti-inflammatory activity  PTP1B inhibitory activity  Structure-activity relationship  
Identification of Potential Biomarkers from Aconitum carmichaelii, a Traditional Chinese Medicine, Using a Metabolomic Approach 期刊论文
PLANTA MEDICA, 2018, 卷号: 84, 期号: 6-7, 页码: 434-441
作者:  Zhao, Dake;  Shi, Yana;  Zhu, Xinyan;  Liu, Li;  Ji, Pengzhang;  Long, Chunlin;  Shen, Yong;  Kennelly, Edward J.
浏览  |  Adobe PDF(228Kb)  |  收藏  |  浏览/下载：254/67  |  提交时间：2018/07/02
Aconitum  Aconitum Carmichaelii  Ranunculaceae  Aconitum Alkaloids  Diterpene Alkaloids  Analgesic Activity  Acute Toxicity  Traditional Chinese Medicine  Tcm  
Potent anti-inflammatory and analgesic steroidal alkaloids from Veratrum taliense 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 179, 页码: 274-279
作者:  Li, Qiong;  Yang, Kun-Xian;  Zhao, Yun-Li;  Qin, Xu-Jie;  Yang, Xing-Wei;  Liu, Lu;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：269/93  |  提交时间：2016/06/27
Pimacao  V. Taliense  Steroidal Alkaloids  Anti-inflammatory  Analgesic  
Four new C-18-diterpenoid alkaloids with analgesic activity from Aconitum weixiense 期刊论文
FITOTERAPIA, 2013, 卷号: 91, 页码: 280-283
作者:  Zhao, Da-Ke;  Ai, Hong-Lian;  Zi, Shu-Hui;  Zhang, Li-Mei;  Yang, Sheng-Chao;  Guo, Hua-Chun;  Shen, Yong;  Chen, Yan-Ping;  Chen, Ji-Jun
浏览  |  Adobe PDF(323Kb)  |  收藏  |  浏览/下载：495/107  |  提交时间：2014/01/13
Diterpenoid Alkaloids  Weisaconitines A-d  Analgesic Activity  Aconitum Weixiense  Ranunculaceae