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Dispersal modes affect Rhamnaceae diversification rates in a differentiated manner 期刊论文
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2023, 卷号: 290, 期号: 2011, 页码: 20231926
作者:  Chen,Yong-Sheng;  Muellner-Riehl,Alexandra N.;  Yang,Yi;  Liu,Jian;  Dimitrov,Dimitar;  Luo,Ao;  Luo,Yuan;  Sun,Hang;  Wang,Zhi-Heng
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：45/6  |  提交时间：2024/07/17
dispersal mode  diversification rate  extinction  Rhamnaceae  speciation  TRAIT-DEPENDENT SPECIATION  LONG-DISTANCE DISPERSAL  SEED DISPERSAL  HISTORICAL BIOGEOGRAPHY  PHYLOGENETIC ANALYSIS  NICHE EVOLUTION  FRUIT EVOLUTION  POMADERREAE  SHIFTS  GENUS  
Guvermectin Biosynthesis Revealing the Key Role of a Phosphoribohydrolase and Structural Insight into the Active Glutamate of a Noncanonical Adenine Phosphoribosyltransferase 期刊论文
ACS CHEMICAL BIOLOGY, 2023
作者:  Liu,Chongxi;  Wang,Zhiyan;  Chen,Yin;  Yan,Yijun;  Li,Lei;  Wang,Yong-Jiang;  Bai,Lu;  Li,Shanshan;  Zhang,Yanyan;  Wang,Xiangjing;  Huang,Sheng-Xiong;  Xiang,Wensheng
浏览  |  Adobe PDF(4470Kb)  |  收藏  |  浏览/下载：60/8  |  提交时间：2024/07/10
CRYSTAL-STRUCTURE  GENOMES  
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：110/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Genomic and structural basis for evolution of tropane alkaloid biosynthesis 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 17, 页码: e2302448120
作者:  Wang,Yong-Jiang;  Tain,Tian;  Yu,Jia-Yi;  Li,Jie;  Xu,Bingyan;  Chen,Jianghua;  D'Auria,John C.;  Huang,Jian-Ping;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(2613Kb)  |  收藏  |  浏览/下载：61/19  |  提交时间：2024/05/09
tropane alkaloids  evolution  biosynthesis  genome  structural biology  METHYLTRANSFERASE  REVEAL  
Editorial: Metabolism of plant natural products proceedings of annual meeting of CSPB2021 期刊论文
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1120573
作者:  Huang,Sheng-Xiong;  Qi,Xiaoquan;  Wang,Yong
浏览  |  Adobe PDF(261Kb)  |  收藏  |  浏览/下载：60/8  |  提交时间：2024/05/09
metabolism  natural product  bioactive compounds  biosynthesis  metabolomics  
Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4994
作者:  Tian, Tian;  Wang, Yong-Jiang;  Huang, Jian-Ping;  Li, Jie;  Xu, Bingyan;  Chen, Yin;  Wang, Li;  Yang, Jing;  Yan, Yijun;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1664Kb)  |  收藏  |  浏览/下载：86/22  |  提交时间：2024/04/30
TROPANE ALKALOID BIOSYNTHESIS  CHAIN-LENGTH CONTROL  
The effects of changes in flowering plant composition caused by nitrogen and phosphorus enrichment on plant-pollinator interactions in a Tibetan alpine grassland 期刊论文
FRONTIERS IN PLANT SCIENCE, 2022, 卷号: 13, 页码: 964109
作者:  Wang, Lin-Lin;  Ren, Fei;  Zhang, Chan;  Huang, Xiao-Juan;  Zhang, Zhen-Hua;  He, Jin-Sheng;  Yang, Yong-Ping;  Duan, Yuan-Wen
浏览  |  Adobe PDF(6005Kb)  |  收藏  |  浏览/下载：40/12  |  提交时间：2024/08/21
climate change  grassland ecosystems  biodiversity loss  nutrition addition  pollination network  Qinghai-Tibet Plateau  BIODIVERSITY LOSS  NUTRIENT ENRICHMENT  SPECIES LOSS  LIMITATION  DEPOSITION  RESOURCES  COMMUNITY  SPECIALIZATION  DETERMINANTS  DECLINES  
Discovery and Engineering of the Cocaine Biosynthetic Pathway 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022
作者:  Wang, Yong-Jiang;  Huang, Jian-Ping;  Tian, Tian;  Yan, Yijun;  Chen, Yin;  Yang, Jing;  Chen, Jianghua;  Gu, Yu-Cheng;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(3096Kb)  |  收藏  |  浏览/下载：252/31  |  提交时间：2024/08/21
TROPANE ALKALOID BIOSYNTHESIS  ERYTHROXYLUM COCA  METHYLATION  STEP  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：111/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Tropane alkaloid biosynthesis: a centennial review 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 9, 页码: 1634-1658
作者:  Huang,Jian-Ping;  Wang,Yong-Jiang;  Tian,Tian;  Wang,Li;  Yan,Yijun;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(2786Kb)  |  收藏  |  浏览/下载：178/43  |  提交时间：2022/04/02
PUTRESCINE N-METHYLTRANSFERASE  TRANSFORMED ROOT CULTURES  2 TROPINONE REDUCTASES  ROLLE DES ACETATS  DATURA-STRAMONIUM  HYOSCYAMUS-NIGER  TOBACCO ALKALOIDS  ORNITHINE-DECARBOXYLASE  2-OXOGLUTARATE-DEPENDENT DIOXYGENASE  DIFFERENT STEREOSPECIFICITIES