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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2023, 卷号: 18, 期号: 7
作者:  Xu,Wenqiang;  Sun,Tian-Yu;  Di,Yingtong;  Hao,Xiaojiang;  Wu,Yun-Dong
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alkaloids  chemical synthesis  inverse-electron demanding Diels-Alder reaction  reaction mechanisms  theoretical study  BIOMIMETIC TOTAL-SYNTHESIS  CORRELATED MOLECULAR CALCULATIONS  MARINE-DERIVED FUNGUS  GAUSSIAN-BASIS SETS  (-)-VERSICOLAMIDE B  ORBITAL METHODS  BREVIANAMIDE-A  STEPHACIDIN-A  MODEL  CONCISE  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
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Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Four new Myrioneuron alkaloids from Mycetia effusa (Myrioneuron effusum) 期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 53, 页码: 175-178
作者:  Li,Xiao-Hui;  Zhang,Jia-Hui;  Zhang,Yu;  Di,Ying-Tong;  Gu,Yu-Cheng;  Cao,Mingming;  Hao,Xiao-Jiang
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Mycetia effuse  Myrioneuron effusum  Rubiaceae  Myrioneuron alkaloids  SKELETON  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
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ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
A clue to the evolutionary history of modern East Asian flora: Insights from phylogeography and diterpenoid alkaloid distribution pattern of the Spiraea japonica complex 期刊论文
MOLECULAR PHYLOGENETICS AND EVOLUTION, 2023, 卷号: 184, 页码: 107772
作者:  Luo,Dong;  Song,Min-shu;  Xu,Bo;  Zhang,Yu;  Zhang,Jian-wen;  Ma,Xiang-guang;  Hao,Xiao jiang;  Sun,Hang
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ampliative Spiraea japonica complex  East Asian flora  Transition belt  Phylogeography  Diterpenoid alkaloids  MOLECULAR PHYLOGEOGRAPHY  SECONDARY METABOLITES  HENGDUAN MOUNTAINS  QUATERNARY CLIMATE  PLANT DIVERSITY  ROSACEAE  DNA  CHLOROPLAST  COALESCENT  CHINA  
Correction: Uncarialines A-E, new alkaloids from Uncaria rhynchophylla and their anticoagulant activity. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 15-15
作者:  Huang, Ke-Pu;  Xu, Li-Li;  Li, Sheng;  Wei, Yin-Ling;  Yang, Lian;  Hao, Xiao-Jiang;  He, Hong-Ping;  Zhang, Yu
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Uncarialines A-E, new alkaloids from Uncaria rhynchophylla and their anticoagulant activity. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 13-13
作者:  Huang, Ke-Pu;  Xu, Li-Li;  Li, Sheng;  Wei, Yin-Ling;  Yang, Lian;  Hao, Xiao-Jiang;  He, Hong-Ping;  Zhang, Yu
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The Aqueous Extract of Brassica oleracea L. Exerts Phytotoxicity by Modulating H2O2 and O2Levels, Antioxidant Enzyme Activity and Phytohormone Levels 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 17, 页码: 3086
作者:  Wang,Yu;  Zhao,Yuanzheng;  Dong,Baozhu;  Wang,Dong;  Hao,Jianxiu;  Jia,Xinyu;  Zhao,Yuxi;  Nian,Yin;  Zhou,Hongyou
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allelopathy  reactive oxygen species  antioxidant enzymes  phytohormones  LC-MS  AUXIN  ESTER  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE