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The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein 期刊论文
CELL DEATH AND DIFFERENTIATION, 2020, 卷号: 27, 期号: 2, 页码: 632-645
作者:  Hua, Xiaohui;  Huang, Maowen;  Deng, Xu;  Xu, Jiheng;  Luo, Yisi;  Xie, Qipeng;  Xu, Jiawei;  Tian, Zhongxian;  Li, Jingxia;  Zhu, Junlan;  Huang, Chao;  Zhao, Qin-shi;  Huang, Haishan;  Huang, Chuanshu
收藏  |  浏览/下载：451/0  |  提交时间：2020/03/24
New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer 期刊论文
CANCER LETTERS, 2018, 卷号: 436, 页码: 38-51
作者:  Hua, Xiaohui;  Xua, Jiheng;  Deng, Xu;  Xu, Jiawei;  Li, Jingxia;  Zhu, David Q.;  Zhu, Junlan;  Jin, Honglei;  Tian, Zhongxian;  Huang, Haishan;  Zhao, Qin-shi;  Huang, Chuanshu
收藏  |  浏览/下载：298/0  |  提交时间：2018/11/12
Anchorage-independent growth  Cheliensisine A-fluoride (Ch1A-F)  Macro-autophagy (autophagy)  miR-27a  Sestrin-2  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
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Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Biomimetic synthesis of (-)-chaetominine epimers via copper-catalyzed radical cyclization 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 22, 页码: 3699-3704
作者:  Deng, Xu;  Liang, Kangjiang;  Tong, Xiaogang;  Ding, Ming;  Li, Dashan;  Xia, Chengfeng;  Xia,CF (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  xia-chengfeng@mail.kib.ac.cn
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Indole Alkaloids  (-)-chaetominine  Total Synthesis  Copper-catalyzed  Cyclization  
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
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Copper-Mediated Dimerization to Access 3a,3a '-'Bispyrrolidinoindoline: Diastereoselective Synthesis of (+)-WIN 64821 and (-)-Ditryptophenaline 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 2, 页码: 206-209
作者:  Liang, Kangjiang;  Deng, Xu;  Tong, Xiaogang;  Li, Dashan;  Ding, Ming;  Zhou, Ankun;  Xia, Chengfeng;  Xia,CF (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  xiachengfeng@mail.kib.ac.cn
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Construction of Tetracyclic 3-Spirooxindole through Cross-Dehydrogenation of Pyridinium: Applications in Facile Synthesis of (+/-)-Corynoxine and (+/-)-Corynoxine B 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 卷号: 136, 期号: 52, 页码: 17962-17965
作者:  Xu, Jun;  Shao, Li-Dong;  Li, Dashan;  Deng, Xu;  Liu, Yu-Chen;  Zhao, Qin-Shi;  Xia, Chengfeng
浏览  |  Adobe PDF(696Kb)  |  收藏  |  浏览/下载：640/96  |  提交时间：2015/06/17
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
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Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：372/83  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
New alkaloids sinomacutines A-E, and cephalonine-2-O-beta-D-glucopyranoside from rhizomes of Sinomenium acutum 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8893-8899
作者:  Li, Yan-Hong;  Li, Hong-Mei;  Li, Yan;  He, Juan;  Deng, Xu;  Peng, Li-Yan;  Gao, Ling-Huan;  Zhao, Qin-Shi;  Li, Rong-Tao;  Wu, Xing-De;  Li,RT (reprint author),Kunming Univ Sci & Technol,Fac Life Sci & Technol,Kunming 650500,Yunnan,Peoples R China.;  rongtaolikm@gmail.com;  wuxingde@mail.kib.ac.cn
浏览  |  Adobe PDF(673Kb)  |  收藏  |  浏览/下载：331/97  |  提交时间：2015/01/20
Sinomenium Acutum  Bistetrahydroisoquinoline Alkaloid  Acid Hydrolysis  Cytotoxicity  Anti-inflammatory Activity