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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
浏览  |  Adobe PDF(4052Kb)  |  收藏  |  浏览/下载：203/13  |  提交时间：2022/04/02
cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
作者:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
浏览  |  Adobe PDF(4101Kb)  |  收藏  |  浏览/下载：224/21  |  提交时间：2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：528/117  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：362/123  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 9, 页码: 1208-1217
作者:  Su, Xing-li;  Su, Wen;  Wang, Ying;  Wang, Yue-hu;  Ming, Xin;  Kong, Yi
浏览  |  Adobe PDF(2212Kb)  |  收藏  |  浏览/下载：289/98  |  提交时间：2017/01/05
Psm2  Selaginellaceae  Pyrrolidinoindoline Alkaloid  Antiplatelet  Antithrombosis  Pi3k/akt Signaling  
Biodiversity in cultivated Panax notoginseng populations 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 9, 页码: 1137-1140
作者:  Wang, Dong;  Hong, Deborah;  Koh, Hwee-ling;  Zhang, Ying-jun;  Yang, Chong-ren;  Hong, Yan
Adobe PDF(768Kb)  |  收藏  |  浏览/下载：466/132  |  提交时间：2011/12/19
Panax Notoginseng  Aflp  Genetic Diversity  Phenotypes  Saponins  Breeding  
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 6, 页码: 752-758
作者:  Yan, Jian-hua;  Li, Qun-yi;  Boutin, Jean A.;  Renard, M. Pierre;  Ding, Yi-xiang;  Hao, Xiao-jiang;  Zhao, Wei-min;  Wang, Ming-wei
Adobe PDF(435Kb)  |  收藏  |  浏览/下载：524/150  |  提交时间：2011/12/19
Melanin-concentrating Hormone  Melanin-concentrating Hormone Receptor-1  Antagonist  
Effects of geraniin on osteoporosis and osteoclastic bone resorption 期刊论文
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 页码: 287-288
作者:  Wu, Ying;  Li, Malin;  Chen, Peng;  Lei, Weiya;  Liu, Jikai;  Shen, Zhiqiang
收藏  |  浏览/下载：235/0  |  提交时间：2012/07/25
Geraniin  Osteoporosis  Osteoclasts  Bone Resorption  
PAI-1 and tPA modulating activity and thrombolytic effects of cytochalasine D 会议论文
ACTA PHARMACOLOGICA SINICA
作者:  Shen, Zhiqiang;  Li, Malin;  Chen, Peng;  Lei, Weiya;  Liu, Jikai
收藏  |  浏览/下载：356/0  |  提交时间：2012/07/25
Cytochalasine d  Thrombolysis  Tpa  Pai-1  
Induction of leukemia cell apoptosis by cheliensisin A involves down-regulation of Bcl-2 expression 期刊论文
ACTA PHARMACOLOGICA SINICA, 2005, 卷号: 26, 期号: 5, 页码: 623-628
作者:  Zhong, L;  Li, CM;  Hao, XJ;  Lou, LG
浏览  |  Adobe PDF(6986Kb)  |  收藏  |  浏览/下载：283/56  |  提交时间：2012/07/25
Goniothalamus Cheliensis  Cheliensisin a  Apoptosis  Hl-60 Cells  Bcl-2 Genes  Cyclic Amp-dependent Protein Kinases  Caspases