| The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling | |
Su, Xing-li1; Su, Wen1; Wang, Ying1; Wang, Yue-hu3,4 ; Ming, Xin5; Kong, Yi1,2
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| 2016-09-01 | |
| 发表期刊 | ACTA PHARMACOLOGICA SINICA
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| 卷号 | 37期号:9页码:1208-1217 |
| 摘要 | Aim: Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further evaluated the antiplatelet effects of Psm2, and elucidated the underlying mechanisms. |
| 关键词 | Psm2 Selaginellaceae Pyrrolidinoindoline Alkaloid Antiplatelet Antithrombosis Pi3k/akt Signaling |
| DOI | 10.1038/aps.2016.52 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000383046000007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/33589 |
| 专题 | 资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.China Pharmaceut Univ, Sch Life Sci & Technol, Nanjing 210009, Peoples R China 2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Peoples R China 3.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 4.Chinese Acad Sci, Yunnan Key Lab Wild Plant Resources, Kunming Inst Bot, Kunming 650201, Peoples R China 5.Univ North Carolina Chapel Hill, UNC Eshelman Sch Pharm, Div Mol Pharmaceut, Chapel Hill, NC 27599 USA |
| 推荐引用方式 GB/T 7714 | Su, Xing-li,Su, Wen,Wang, Ying,et al. The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling[J]. ACTA PHARMACOLOGICA SINICA,2016,37(9):1208-1217. |
| APA | Su, Xing-li,Su, Wen,Wang, Ying,Wang, Yue-hu,Ming, Xin,&Kong, Yi.(2016).The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling.ACTA PHARMACOLOGICA SINICA,37(9),1208-1217. |
| MLA | Su, Xing-li,et al."The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling".ACTA PHARMACOLOGICA SINICA 37.9(2016):1208-1217. |
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| su2016.pdf（2212KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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