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NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 220, 页码: 220-227
作者:  Zeng, Guang-Zhi;  Wang, Zhe;  Zhao, Li-Mei;  Fan, Jun-Ting;  Tan, Ning-Hua
收藏  |  浏览/下载:204/0  |  提交时间:2018/07/16
Rubiarbonol g  Rubia Yunnanensis  Cytotoxicity  Mechanism  
两种茜草属植物中的环肽及其它成分研究 学位论文
: 中国科学院大学, 2016
作者:  黄茂波
Adobe PDF(6568Kb)  |  收藏  |  浏览/下载:105/8  |  提交时间:2018/08/23
三种茜草属植物中环肽和其他成分及生物活性研究 学位论文
, 昆明: 中国科学院大学, 2015
作者:  赵思蒙
Adobe PDF(10750Kb)  |  收藏  |  浏览/下载:384/19  |  提交时间:2017/06/09
茜草属  金剑草  多花茜草  钩毛茜草  茜草科类型环肽  萘醌二聚体  Nf-κb信号通路  分子对接  药效团  
茜草和林生茜草中环肽及其它化学成分研究 学位论文
, 北京: 中国科学院大学, 2015
作者:  陈小强
Adobe PDF(5428Kb)  |  收藏  |  浏览/下载:374/17  |  提交时间:2016/06/24
茜草属植物  茜草  林生茜草  茜草科类型环肽  化学成分  细胞毒  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
Adobe PDF(6299Kb)  |  收藏  |  浏览/下载:255/43  |  提交时间:2015/05/14
One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 6, 页码: 1213-1225
作者:  Zhao Simeng;  Kuang Bin;  Peng Wenwen;  He Wenjun;  Xu Huimin;  Ji Changjiu;  Han Jing;  Zheng Yuqing;  Song Weiwu;  Tan Ninghu
Adobe PDF(522Kb)  |  收藏  |  浏览/下载:333/76  |  提交时间:2014/04/02
Cyclopeptide  Traditional Chinese Medicine  Chemical Constituent  
大叶茜草的化学成分及其活性研究 学位论文
: 中国科学院研究生院, 2012
作者:  邝彬
Adobe PDF(2402Kb)  |  收藏  |  浏览/下载:251/13  |  提交时间:2015/03/23
Biologically Active Arborinane-Type Triterpenoids and Anthraquinones from Rubia yunnanensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2011, 卷号: 74, 期号: 10, 页码: 2069-2080
作者:  Fan, Jun-Ting;  Kuang, Bin;  Zeng, Guang-Zhi;  Zhao, Si-Meng;  Ji, Chang-Jiu;  Zhang, Yu-Mei;  Tan, Ning-Hua
Adobe PDF(1532Kb)  |  收藏  |  浏览/下载:387/163  |  提交时间:2012/04/10
Nitric-oxide Production  Bioactive Constituents  Cyclic Hexapeptides  Cordifolia  Acid  Rubiyunnanins  Derivatives  Inhibitors  Roots  
小红参抗肿瘤环肽及其作用机制研究  学位论文
: 中国科学院研究生院, 2010
范君婷 
Adobe PDF(6007Kb)  |  收藏  |  浏览/下载:468/24  |  提交时间:2013/01/28
9,10-Anthraquinones and Other Biologically Active Compounds from theGenus Rubia 期刊论文
CHEMISTRY & BIODIVERSITY, 2004, 卷号: 1, 页码: 1241-1264
作者:  Cunxi Wang;  Sergei Avdiushko;  David F. Hildebrand
Adobe PDF(592Kb)  |  收藏  |  浏览/下载:21/0  |  提交时间:2017/07/19