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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：302/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 2574
作者:  Zhang, Xing-Jie;  Wang, Rui-Rui;  Chen, Huan;  Luo, Rong-Hua;  Yang, Liu-Meng;  Liu, Jing-Ping;  Sun, Han-Dong;  Zhang, Hong-Bin;  Xiao, Wei-Lie;  Zheng, Yong-Tang
浏览  |  Adobe PDF(2175Kb)  |  收藏  |  浏览/下载：380/27  |  提交时间：2018/05/08
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：216/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
大萼香茶菜乙素二乙酰化物的药物新用途 专利
申请日期: 2017-10-16, 公开日期: 2018-02-02
发明人:  赫捷;  普建新;  王婧男;  孙汉董;  孙楠;  吴海燕;  高亦博
Adobe PDF(3053Kb)  |  收藏  |  浏览/下载：145/0  |  提交时间：2018/05/10
细锥香茶菜乙素在制备抑制食管鳞癌细胞增殖的产品中的应用 专利
申请日期: 2017-05-05, 公开日期: 2017-09-29
发明人:  赫捷;  普建新;  陈照丽;  孙汉董;  王婧男;  吴海燕
Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：190/0  |  提交时间：2018/05/10
Comprehensive quantitative analysis of Chinese patent drug YinHuang drop pill by ultra high-performance liquid chromatography quadrupole time of flight mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 卷号: 125, 期号: 1, 页码: 415-426
作者:  Wong,Tin-Long;  An,Ya-Qi;  Yan,Bing-Chao;  Yue,Rui-Qi;  Zhang,Tian-Bo;  Ho,Hing-Man;  Ren,Tian-Jing;  Fung,Hau-Yee;  Ma,Dik-Lung;  Leung,Chung-Hang;  Liu,Zhong-Liang;  Pu,Jian-Xin;  Han,Quan-Bin;  Sun,Han-Dong
浏览  |  Adobe PDF(1970Kb)  |  收藏  |  浏览/下载：212/61  |  提交时间：2017/07/11
SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry 期刊论文
BMC MICROBIOLOGY, 2015, 卷号: 15
作者:  Bai,Ru;  Zhang,Xing-Jie;  Li,Yan-Li;  Liu,Jing-Ping;  Zhang,Hong-Bin;  Xiao,Wei-Lie;  Pu,Jian-Xin;  Sun,Han-Dong;  Zheng,Yong-Tang;  Liu,Li-Xin
浏览  |  Adobe PDF(2540Kb)  |  收藏  |  浏览/下载：207/52  |  提交时间：2016/01/19
Hiv-1  Pre-integration Complex  Nuclear Entry  Capsid  Sjp-l-5  
Diterpene Alkaloids with an Aza-ent-kaurane Skeleton from Isodon rubescens 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 2, 页码: 196-201
作者:  Liu, Xu;  Yang, Jing;  Wang, Wei-Guang;  Li, Yan;  Wu, Ji-Zhou;  Pu, Jian-Xin;  Sun, Han-Dong;  Pu,JX (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  pujianxin@mail.kib.ac.cn;  hdsun@mail.kib.ac.cn
浏览  |  Adobe PDF(1517Kb)  |  收藏  |  浏览/下载：276/68  |  提交时间：2015/06/29
Two Natural ent-kauranoids as Novel Wnt Signaling Inhibitors. 期刊论文
Natural products and bioprospecting, 2014, 卷号: 4, 期号: 3, 页码: 135-40
作者:  Zhang, Jing;  Kong, Ling-Mei;  Zhan, Rui;  Ye, Zhen-Nan;  Pu, Jian-Xin;  Sun, Han-Dong;  Li, Yan
收藏  |  浏览/下载：93/0  |  提交时间：2019/03/29
Five New Nortriterpenoids from the Stems of Schisandra neglecta 期刊论文
HELVETICA CHIMICA ACTA, 2013, 卷号: 96, 期号: 7, 页码: 1376-1385
作者:  Liang, Cheng-Qin;  Hu, Jing;  Shi, Yi-Ming;  Shang, Shan-Zhai;  Du, Xue;  Zhan, Rui;  Wang, Wei-Guang;  Xiong, Wen-Yong;  Xiao, Wei-Lie;  Zhang, Hong-Bin;  Sun, Han-Dong
Adobe PDF(407Kb)  |  收藏  |  浏览/下载：358/89  |  提交时间：2014/01/13
Schisandra Neglecta  Nortriterpenoids  Triterpenoids  Insulin Sensitivity  Schicagenins D-f  Negleschidilactones a And b