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Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：233/70  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：254/59  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Chemical constituents from the whole herb of Hemiphragma heterophyllum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 6, 页码: 551-558
作者:  Dai, Jia-Meng;  Li, Yan-Hong;  Pu, Xiao-Yun;  Yang, Cui;  Sun, Jing-Xian;  Ruan, Roger;  Li, Xiao-Nian;  Tian, Kai;  Huang, Xiang-Zhong
浏览  |  Adobe PDF(1086Kb)  |  收藏  |  浏览/下载：256/29  |  提交时间：2019/06/24
Scrophulariaceae  Hemiphragma heterophyllum  sesquineolignans  iridoids  alpha-glucosidase inhibitory activity  
Arahyside A, a new norsesquiterpene from Arachis hypogaea 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 4
作者:  Jin, Wen-Fang;  Luo, Zheng-Hui;  Sun, Yun-Peng;  Liu, Jin-Song;  Yu, Yang;  Wang, Gang;  Wang, Guo-Kai
浏览  |  Adobe PDF(782Kb)  |  收藏  |  浏览/下载：136/25  |  提交时间：2019/07/29
Arachis hypogaea  norsesquiterpene  arahyside A  cytotoxic activity  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：293/64  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 1, 页码: 45-50
作者:  Feng, Tao;  Gan, Xiao-Qing;  Zhao, Yun-Li;  Zhang, Shuai-Bing;  Chen, He-Ping;  He, Juan;  Zheng, Yong-Sheng;  Sun, Huan;  Huang, Rong;  Li, Zheng-Hui;  Liu, Ji-Kai
浏览  |  Adobe PDF(1583Kb)  |  收藏  |  浏览/下载：232/66  |  提交时间：2019/03/18
Indole and flavonoid from the herbs of Kalimeris shimadai 期刊论文
PHYTOCHEMISTRY LETTERS, 2018, 卷号: 28, 页码: 135-138
作者:  Zhang, Nan;  Jin, Wen-Fang;  Sun, Yun-Peng;  Wang, Gang;  Yu, Yang;  Zhou, Zhong-Yu;  Wang, Guo-Kai;  Liu, Jin-Song
收藏  |  浏览/下载：299/0  |  提交时间：2018/12/18
Kalimeris shimadai  Indole  Flavonoid  Cytotoxicity  
Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 46, 页码: 4063-4066
作者:  Yan, Chen;  Zhang, Wei-Qing;  Sun, Mao;  Liang, Wei;  Wang, Tian-Yuan;  Zhang, Yun-Dong;  Ding, Xiao
收藏  |  浏览/下载：275/0  |  提交时间：2018/12/18
Carpesium cernuum  Sesquiterpene  SMMC-7721 cancer cells  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：213/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：258/93  |  提交时间：2017/10/23
Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins