Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum

	Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum
	Feng, Tao 1; Gan, Xiao-Qing 1; Zhao, Yun-Li 2; Zhang, Shuai-Bing 1; Chen, He-Ping 1; He, Juan 1; Zheng, Yong-Sheng 1; Sun, Huan 1; Huang, Rong1 ; Li, Zheng-Hui 1; Liu, Ji-Kai 1
	2019
Source Publication	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
Volume	82 Issue:1 Pages:45-50
Abstract	Two new Tricholoma terpenoids, tricholopardins A and B, were isolated from the fruiting bodies of the basidiomycetes Tricholoma pardinum. Their structures were elucidated by spectroscopic methods, as well as electronic circular dichroism and optical rotatory dispersion calculations. Tricholopardin A potently inhibited nitric oxide production in lipopolysaccharide-induced RAW264.7 macrophages with an IC50 of 0.08 mu M. Its anti-inflammatory effects on three inflammatory mediators were also evaluated. A plausible biosynthetic pathway for these products is discussed.
Indexed By	SCI
Language	英语
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/64190
Collection	植物化学与西部植物资源持续利用国家重点实验室
Corresponding Author	Li, Zheng-Hui; Liu, Ji-Kai
Affiliation	1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation GB/T 7714	Feng, Tao,Gan, Xiao-Qing,Zhao, Yun-Li,et al. Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum[J]. JOURNAL OF NATURAL PRODUCTS,2019,82(1):45-50.
APA	Feng, Tao.,Gan, Xiao-Qing.,Zhao, Yun-Li.,Zhang, Shuai-Bing.,Chen, He-Ping.,...&Liu, Ji-Kai.(2019).Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum.JOURNAL OF NATURAL PRODUCTS,82(1),45-50.
MLA	Feng, Tao,et al."Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum".JOURNAL OF NATURAL PRODUCTS 82.1(2019):45-50.

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