Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum
Feng, Tao1; Gan, Xiao-Qing1; Zhao, Yun-Li2; Zhang, Shuai-Bing1; Chen, He-Ping1; He, Juan1; Zheng, Yong-Sheng1; Sun, Huan1; Huang, Rong1; Li, Zheng-Hui1; Liu, Ji-Kai1
2019
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume82Issue:1Pages:45-50
AbstractTwo new Tricholoma terpenoids, tricholopardins A and B, were isolated from the fruiting bodies of the basidiomycetes Tricholoma pardinum. Their structures were elucidated by spectroscopic methods, as well as electronic circular dichroism and optical rotatory dispersion calculations. Tricholopardin A potently inhibited nitric oxide production in lipopolysaccharide-induced RAW264.7 macrophages with an IC50 of 0.08 mu M. Its anti-inflammatory effects on three inflammatory mediators were also evaluated. A plausible biosynthetic pathway for these products is discussed.
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64190
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorLi, Zheng-Hui; Liu, Ji-Kai
Affiliation1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China
2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Feng, Tao,Gan, Xiao-Qing,Zhao, Yun-Li,et al. Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum[J]. JOURNAL OF NATURAL PRODUCTS,2019,82(1):45-50.
APA Feng, Tao.,Gan, Xiao-Qing.,Zhao, Yun-Li.,Zhang, Shuai-Bing.,Chen, He-Ping.,...&Liu, Ji-Kai.(2019).Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum.JOURNAL OF NATURAL PRODUCTS,82(1),45-50.
MLA Feng, Tao,et al."Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum".JOURNAL OF NATURAL PRODUCTS 82.1(2019):45-50.
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