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Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：252/72  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Airways antiallergic effect and pharmacokinetics of alkaloids from Alstonia scholaris 期刊论文
PHYTOMEDICINE, 2017, 卷号: 27, 页码: 63-72
作者:  Zhao, Yun-Li;  Cao, Jing;  Shang, Jian-Hua;  Liu, Ya-Ping;  Khan, Afsar;  Wang, Heng-Shan;  Qian, Yi;  Liu, Lu;  Ye, Min;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：247/54  |  提交时间：2017/06/01
Scholaricine  19-epischolaricine  Vallesamine  Picrinine  Pharmacokinetic  Asthma  
Characterization of chemical constituents and rats metabolites of an alkaloidal extract of Alstonia scholaris leaves by liquid chromatography coupled with mass spectrometry 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1026, 页码: 43-55
作者:  Cao, Jing;  Shen, Hong-Mei;  Wang, Qi;  Qian, Yi;  Guo, Hong-Cheng;  Li, Kai;  Qiao, Xue;  Guo, De-An;  Luo, Xiao-Dong;  Ye, Min
浏览  |  Adobe PDF(3284Kb)  |  收藏  |  浏览/下载：271/97  |  提交时间：2016/09/28
Alstonia Scholaris  Alkaloids  Uhplc/qtof-ms  Metabolites Identification  Herbal Medicine  
Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway 期刊论文
CELL DEATH & DISEASE, 2013, 卷号: 4, 页码: e804
作者:  Deng, Q.;  Yu, X.;  Xiao, L.;  Hu, Z.;  Luo, X.;  Tao, Y.;  Yang, L.;  Liu, X.;  Chen, H.;  Ding, Z.;  Feng, T.;  Tang, Y.;  Weng, X.;  Gao, J.;  Yi, W.;  Bode, A. M.;  Dong, Z.;  Liu, J.;  Cao, Y.
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载：630/73  |  提交时间：2013/11/12
Neoalbaconol  Pdk1  Pi3-k/akt  Energy Depletion  Cancer Cell Death  
Microfractionation bioactivity-based ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of nuclear factor-kappa B inhibitors and beta(2) adrenergic receptor agonists in an alkaloidal extract of the folk herb Alstonia scholaris 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 卷号: 908, 页码: 98-104
作者:  Hou, Yuanyuan;  Cao, Xuelin;  Wang, Liqiang;  Cheng, Binfeng;  Dong, Linyi;  Luo, Xiaodong;  Bai, Gang;  Gao, Wenyuan
Adobe PDF(764Kb)  |  收藏  |  浏览/下载：325/92  |  提交时间：2013/01/22
Dual-bioactivity-integrated Fingerprinting  Constituent Identification  Nuclear Factor-kappa b Inhibitor  Beta(2) Adrenergic Receptor Agonist  Ultra Performance Liquid Chromatography/quadrupole Time-of-flight Mass Spectrometry  
Bioactivity-based liquid chromatography-coupled electrospray ionization tandem ion trap/time of flight mass spectrometry for beta(2)AR agonist identification in alkaloidal extract of Alstonia scholaris 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2012, 卷号: 1227, 页码: 203-209
作者:  Hou, Yuanyuan;  Cao, Xuelin;  Dong, Linyi;  Wang, Liqiang;  Cheng, Binfeng;  Shi, Qian;  Luo, Xiaodong;  Bai, Gang
Adobe PDF(949Kb)  |  收藏  |  浏览/下载：544/192  |  提交时间：2012/06/07
Bioactivity-integrated Fingerprinting  Constituent Identification  Beta(2) Adrenergic Receptor Agonist  Lcms-it-tof  
Study of solvents effect on distribution of configurational and conformational isomers of apo-tirucallol theoretically and experimentally 期刊论文
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2008, 卷号: 870, 期号: 1-3, 页码: 72-76
作者:  Ren, Jie;  Cai, Xiang-Hai;  Fan, Hua-Fang;  Cao, Jin-Xing;  Liao, Tou-Geng;  Luo, Xiao-Dong;  Zhu, Hua-Jie
Adobe PDF(319Kb)  |  收藏  |  浏览/下载：515/129  |  提交时间：2011/11/24
Apo-tirucallol Derivatives  B3lyp  Mp2  Configurational Isomer Distribution