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Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：32/8  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(2111Kb)  |  收藏  |  浏览/下载：273/32  |  提交时间：2019/09/10
Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载：387/144  |  提交时间：2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：365/92  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships