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Acylphloroglucinol derivatives from the twigs and leaves of Callistemon salignus 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 14, 页码: 1803-1811
作者:  Qin, Xu-Jie;  Liu, Hui;  Yu, Qian;  Yan, Huan;  Tang, Jin-Feng;  An, Lin-Kun;  Khan, Afsar;  Chen, Qi-Run;  Hao, Xiao-Jiang;  Liu, Hai-Yang
Adobe PDF(1199Kb)  |  收藏  |  浏览/下载：228/69  |  提交时间：2017/06/01
Callistemon Salignus  Acylphloroglucinol  Aeroterpenoid  Antimicrobial Activity  Cytotoxicity  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：301/45  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：618/57  |  提交时间：2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：314/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：560/76  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin  
Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 2, 页码: 1054-1065
作者:  Zhao, Lixia;  He, Feng;  Liu, Haiyang;  Zhu, Yushan;  Tian, Weili;  Gao, Ping;  He, Hongping;  Yue, Wen;  Lei, Xiaobo;  Ni, Biyun;  Wang, Xiaohui;  Jin, Haijing;  Hao, Xiaojiang;  Lin, Jialing;  Chen, Quan
Adobe PDF(2908Kb)  |  收藏  |  浏览/下载：201/45  |  提交时间：2015/06/17
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：280/35  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis