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A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：319/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：630/126  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 259, 期号: 3, 页码: 302-310
作者:  Abbasi, Rashda;  Efferth, Thomas;  Kuhmann, Christine;  Opatz, Till;  Hao, Xiaojiang;  Popanda, Odilia;  Schmezer, Peter
Adobe PDF(738Kb)  |  收藏  |  浏览/下载：473/165  |  提交时间：2012/06/07
Cancer Therapy  Synthetic Lethal  Traditional Chinese Medicine  Xpc  Ercc6  Csb  
Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins 期刊论文
CHEMISTRY & BIOLOGY, 2008, 卷号: 15, 期号: 8, 页码: 863-874
作者:  Zhao, Peiji;  Bai, Linquan;  Ma, Juan;  Zeng, Ying;  Li, Lei;  Zhang, Yirong;  Lu, Chunhua;  Dai, Huanqin;  Wu, Zhaoxian;  Li, Yaoyao;  Wu, Xuan;  Chen, Gang;  Hao, Xiaojiang;  Shen, Yuemao;  Deng, Zixin;  Floss, Heinz G.
Adobe PDF(1375Kb)  |  收藏  |  浏览/下载：362/130  |  提交时间：2011/11/24
Biosynthetic Gene-cluster  Lechevalieria-aerocolonigenes Atcc-39243  Escherichia-coli  3-amino-5-hydroxybenzoic Acid  Actinosynnema-pretiosum  Maytansinoid Antibiotics  Streptomyces Sp  Indolocarbazole  Expression  Substrate  
Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 卷号: 104, 期号: 19, 页码: 8083-8088
作者:  Li, Yanmei;  Wang, Lihua;  Li, Shunlin;  Chen, Xiaoying;  Shen, Yuemao;  Zhang, Zhongkai;  He, Hongping;  Xu, Wenbo;  Shu, Yuelong;  Liang, Guodong;  Fang, Rongxiang;  Hao, Xiaojiang
Adobe PDF(1547Kb)  |  收藏  |  浏览/下载：299/78  |  提交时间：2011/11/24
Antiviral Drugs  Strobilanthes Cusia  Cynanchum Atratum