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Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 265-272
作者:  Liu, Jie-Qing;  Yang, Yuan-Feng;  Li, Xu-Yang;  Liu, En-Qian;  Li, Zhong-Rong;  Zhou, Lin;  Li, Yan;  Qiu, Ming-Hua
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：300/103  |  提交时间：2015/05/14
Jatropha Curcas  Euphorbiaceae  Rhamnofolane Diterpenoids  Cytotoxicity  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：316/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Two dimeric lignans with an unusual alpha,beta-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide production (vol 21, pg 373, 2011) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 19, 页码: 5452-5452
作者:  Zhou, Xiao-Jiang;  Chen, Xiao-Liang;  Li, Xue-Song;  Su, Jia;  He, Jiang-Bo;  Wang, Yue-Hu;  Li, Yan;  Cheng, Yong-Xian
浏览  |  Adobe PDF(253Kb)  |  收藏  |  浏览/下载：249/62  |  提交时间：2013/10/16
New steroids and sesquiterpene from Turraea pubescens 期刊论文
FITOTERAPIA, 2013, 卷号: 90, 页码: 119-125
作者:  Yuan, Chun-Mao;  Tang, Gui-Hua;  Wang, Xiao-Ying;  Zhang, Yu;  Cao, Ming-Ming;  Li, Xiao-Hui;  Li, Yan;  Li, Shun-Lin;  Di, Ying-Tong;  He, Hong-Ping;  Hao, Xiao-Jiang;  Hua, Hui-Ming
Adobe PDF(899Kb)  |  收藏  |  浏览/下载：504/266  |  提交时间：2014/01/13
Turraea Pubescens  Meliaceae  Steroids  Sesquiterpene  Anti-inflammatory  
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：413/154  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：319/68  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载：387/144  |  提交时间：2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents