Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas

	Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas
	Liu, Jie-Qing; Yang, Yuan-Feng; Li, Xu-Yang; Liu, En-Qian; Li, Zhong-Rong; Zhou, Lin; Li, Yan; Qiu, Ming-Hua
	2013-12-01
Source Publication	PHYTOCHEMISTRY
Volume	96 Pages:265-272
Abstract	Twelve rhamnofolane diterpenoids, including curcusecons A-E with unusual seco-rhamnofolane skeletons, curcusones F-J, 4-epi-curcusone E, and 3-dehydroxy-2-epi-caniojane, together with seven known analogues, curcusones A-E, jatrogrossidione, and 2-epi-jatrogrossidione, were isolated from the roots of Jatropha curcas. Their structures were determined by extensive spectroscopic methods, and the relative stereochemistry of curcusecon B was further confirmed by X-ray crystallographic data. Their cytotoxity against five human cancer cells was studied and the results indicated that the dienone system in ring B was essential for cytotoxicity of these compounds. (C) 2013 Elsevier Ltd. All rights reserved.
Keyword	Jatropha Curcas Euphorbiaceae Rhamnofolane Diterpenoids Cytotoxicity
Indexed By	SCI ; IC
Language	英语
WOS ID	WOS:000328869500026
Citation statistics	Cited Times:39[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/19245
Collection	植物化学与西部植物资源持续利用国家重点实验室
Affiliation	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Photochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation GB/T 7714	Liu, Jie-Qing,Yang, Yuan-Feng,Li, Xu-Yang,et al. Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas[J]. PHYTOCHEMISTRY,2013,96:265-272.
APA	Liu, Jie-Qing.,Yang, Yuan-Feng.,Li, Xu-Yang.,Liu, En-Qian.,Li, Zhong-Rong.,...&Qiu, Ming-Hua.(2013).Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas.PHYTOCHEMISTRY,96,265-272.
MLA	Liu, Jie-Qing,et al."Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas".PHYTOCHEMISTRY 96(2013):265-272.

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