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Synthesis and structure-activity relationship studies of water-soluble beta-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 328-338
作者:  Liang, Shuobin;  Li, Man;  Yu, Xiaojuan;  Jin, Hongwei;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1284Kb)  |  收藏  |  浏览/下载：243/32  |  提交时间：2019/04/15
Glycyrrhetinic acid  Cyclodextrin  Click reaction  Influenza virus  Inhibitors  
An overview of grayanane diterpenoids and their biological activities from the Ericaceae family in the last seven years 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 400-416
作者:  Li, Chun-Huan;  Zhang, Jia-Yao;  Zhang, Xiu-Yun;  Li, Sheng-Hong;  Gao, Jin-Ming
浏览  |  Adobe PDF(2414Kb)  |  收藏  |  浏览/下载：261/39  |  提交时间：2019/04/15
Grayanane diterpenoids  Ericaceae  Bioactivities  Analgesic activity  Anti-inflammatory activity  PTP1B inhibitory activity  Structure-activity relationship  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：269/80  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 257-269
作者:  Wu, Mingyi;  Wen, Dandan;  Gao, Na;  Xiao, Chuang;  Yang, Lian;  Xu, Li;  Lian, Wu;  Peng, Wenlie;  Jiang, Jianmin;  Zhao, Jinhua;  Jiang,JM (reprint author),Sun Yat Sen Univ,Sch Pharmaceut Sci,Guangzhou 510006,Guangdong,Peoples R China.;  lssjjm@mail.sysu.edu.cn;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(1936Kb)  |  收藏  |  浏览/下载：344/109  |  提交时间：2015/06/29
Fucosylated Chondroitin Sulfate  Factor Xase Inhibitor  Anticoagulant  Antithrombotic  Structure-activity Relationship  
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Yan, Ju-Ming;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Zhou, Bei;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(3339Kb)  |  收藏  |  浏览/下载：351/145  |  提交时间：2013/10/16
Hybrid Compound  Imidazole  Dibenzo[b  Antitumor Activities  d]Furan  Structure-activity Relationships  
Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 111-121
作者:  Wang, Xue-Quan;  Liu, Lan-Xiang;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Li, Liang;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(4369Kb)  |  收藏  |  浏览/下载：302/102  |  提交时间：2013/07/24
Hybrid Compound  2-benzylbenzofuran  Imidazole  Cytotoxic Activities  Structure-activity Relationships  
Protein-based alignment in 3D-QSAR of FBPase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 3, 页码: 885-892
作者:  Yi, Ping;  Di, Ying-Tong;  Liu, Wei;  Hao, Xiao-Jiang;  Ming, Yong;  Huang, Du-Shu;  Yang, Jin;  Yi, Zhong-Zhou;  Li, Zi-Jing;  Yang, Rui-Dong;  Zhang, Ju-Cheng
Adobe PDF(777Kb)  |  收藏  |  浏览/下载：406/165  |  提交时间：2012/04/10
3d-qsar  Gold  Comfa  Fbpase  
3D QSAR studies on ketoamides of human cathepsin K inhibitors based on two different alignment methods 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 45, 期号: 2, 页码: 667-681
作者:  Pan, Xulin;  Tan, Ninghua;  Zeng, Guangzhi;  Huang, Huoqiang;  Yan, He
Adobe PDF(2690Kb)  |  收藏  |  浏览/下载：374/147  |  提交时间：2012/03/21
Cathepsin k  Comfa  Comsia  Ketoamides  
Synthesis and anticancer activity of lipophilic platinum(II) complexes of 3,5-diisopropylsalicylate 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 7, 页码: 1438-1443
作者:  Yu, Yao;  Lou, Li-Guang;  Liu, Wei-Ping;  Zhu, Hua-Jie;  Ye, Qing-Song;  Chen, Xi-Zhu;  Gao, Wen-Gui;  Hou, Shu-Qian
Adobe PDF(432Kb)  |  收藏  |  浏览/下载：1028/282  |  提交时间：2011/12/19
Lipophilic  Platinum(Ii) Complexes  Antitumor Activity  3  5-diisopropylsalicylic Acid  
3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 5, 页码: 925-938
作者:  Yi, Ping;  Fang, Xin;  Qiu, Minghua
Adobe PDF(2704Kb)  |  收藏  |  浏览/下载：323/97  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  Comsia  Checkpoint Kinase Weel