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Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：121/34  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
作者:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
浏览  |  Adobe PDF(5711Kb)  |  收藏  |  浏览/下载：108/33  |  提交时间：2022/04/02
Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载：116/47  |  提交时间：2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载：101/30  |  提交时间：2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：80/13  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN