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Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：419/156  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes  
Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 页码: 243-252
作者:  Yue, Grace G. L.;  Chan, Ben C. L.;  Kwok, Hin-Fai;  Wong, Yuk-Lau;  Leung, Hoi-Wing;  Ji, Chang-Jiu;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
浏览  |  Adobe PDF(1804Kb)  |  收藏  |  浏览/下载：176/48  |  提交时间：2015/05/12
Bigelovin  Inula Helianthus-aquatica  Angiogenesis  Zebrafish  Hmec-1  Cell Adhesion Molecules  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(719Kb)  |  收藏  |  浏览/下载：446/144  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：378/98  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
3D-QSAR and docking studies of aminopyridine carboxamide inhibitors of c-Jun N-terminal kinase-1 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 3, 页码: 604-613
作者:  Yi, Ping;  Qiu, Minghua
Adobe PDF(2801Kb)  |  收藏  |  浏览/下载：305/162  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  C-jun N-terminal Kinase-1  
Natural biflavones as novel inhibitors of cathepsin B and K 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 卷号: 41, 期号: 11, 页码: 1247-1252
作者:  Zeng, G. -Z.;  Pan, X. -L.;  Tan, N. -H.;  Xiong, J.;  Zhang, Y. M.
Adobe PDF(604Kb)  |  收藏  |  浏览/下载：344/149  |  提交时间：2011/11/24
Biflavones  Inhibitors  Cathepsin b  Cathepsin k  Docking