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Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：8/1  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Liu, Hui;  He, Xiao-Zhi;  Feng, Mi-Yan;  Yuan-Zeng;  Rauwolf, Tyler J.;  Shao, Li-Dong;  Ni, Wei;  Yan, Hui;  Porco, John A., Jr.;  Hao, Xiao-Jiang;  Qin, Xu-Jie;  Liu, Hai-Yang
浏览  |  Adobe PDF(3924Kb)  |  收藏  |  浏览/下载：231/72  |  提交时间：2021/01/05
Tsaokopyranols A-M, 2,6-epoxydiarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  He, Xiao-Feng;  Zhang, Xu-Ke;  Geng, Chang-An;  Hu, Jing;  Zhang, Xue-Mei;  Guo, Yuan-Qiang;  Chen, Ji-Jun
浏览  |  Adobe PDF(2442Kb)  |  收藏  |  浏览/下载：119/39  |  提交时间：2021/01/05
ent-Labdane and ent-kaurane diterpenoids from Chelonopsis odontochila with alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Deng, Zhen-Tao;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：134/39  |  提交时间：2021/01/05
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：209/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：339/44  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)