Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects

doi:10.1016/j.phytochem.2019.112065

	Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects
	Fan, Min1,2 ; Luo, Dan 1; Peng, Li-Yan 1; Li, Xiao-Nian 1; Wu, Xing-De 1; Ji, Xu1 ; Zhao, Qin-Shi1
通讯作者	Wu, Xing-De(wuxingde@mail.kib.ac.cn) ; Ji, Xu(jixu@mail.kib.ac.cn) ; Zhao, Qin-Shi(qinshizhao@mail.kib.ac.cn)
	2019-10-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	166 页码:11
摘要	Ten undescribed neo-clerodane diterpenoids, named hispanins A-J, together with six known ones, were isolated from the aerial parts of Salvia hispanica L. Their structures were established by extensive spectroscopic analysis. The absolute configurations of the undescribed compounds were determined by the ECD data and single crystal X-ray diffraction analysis. Hispanins B and C represented the first neo-clerodane diterpenoids with a unique oxygen bridge between C-19 and C-20. All isolated compounds were evaluated for their protective effects against H2O2-induced cardiomyocyte injury. Five of these compounds showed significant cardioprotective effects.
关键词	Salvia hispanica L. (Lamiaceae) Chia Neo-clerodane diterpenoids Hispanins A-J Single crystal X-ray diffraction analysis Cardioprotective effects
DOI	10.1016/j.phytochem.2019.112065
收录类别	SCI
语种	英语
WOS记录号	WOS:000484650500014
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/68630
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Wu, Xing-De; Ji, Xu; Zhao, Qin-Shi
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China 2.Dali Univ, Coll Pharmaceut Sci, Dali 671000, Peoples R China
推荐引用方式 GB/T 7714	Fan, Min,Luo, Dan,Peng, Li-Yan,et al. Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects[J]. PHYTOCHEMISTRY,2019,166:11.
APA	Fan, Min.,Luo, Dan.,Peng, Li-Yan.,Li, Xiao-Nian.,Wu, Xing-De.,...&Zhao, Qin-Shi.(2019).Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects.PHYTOCHEMISTRY,166,11.
MLA	Fan, Min,et al."Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects".PHYTOCHEMISTRY 166(2019):11.

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